PDB ID 1A8M CHAIN A
Protein name TUMOR NECROSIS FACTOR ALPHA
Uniprot Accession P01375
The number of similar proteins 54
The number of binding states 11
The number of binding partners 6
Coloring
Unicolor (beige)
The number of binding partners
Group

Downdload
 Format:  
Molecule viewer
#binding
partners
  6
  5
  4
  3
  2
  1
  0
Sequence information
1   VRSSSRTPSD   KPVAHVVANP   QAEGQLQWLN   DRANALLANG   VELRDNQLVV   50
51   PSEGLYLIYS   QVLFKGQGCP   STHVLLTHTI   SRIAVSYQTK   VNLLSAIKSP   100
101   CQRETPEGAE   AKPWYEPIYL   GGVFQLEKGD   RLSAEINRPD   YLDFAESGQV   150
151   YFGIIAL           200
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
8_PRO LEU VAR_019378 rs4645843 Polymorphism -
18_ALA THR VAR_011927 rs1800620 Polymorphism -
32_ARG TRP ClinVar
chr6:31544934
rs281865419 Pathogenic TNF receptor binding, altered [MedGen:C4016415]