PDB ID 1AJS     CHAIN A
Protein name ASPARTATE AMINOTRANSFERASE
Uniprot Accession P00503
The number of similar proteins 21
The number of binding states 2
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1AJS (CHAIN: A)
1 P00503  
2 Monomeric state

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   APPSVFAEVP   QAQPVLVFKL   IADFREDPDP   RKVNLGVGAY   RTDDCQPWVL   50
51   PVVRKVEQRI   ANNSSLNHEY   LPILGLAEFR   TCASRLALGD   DSPALQEKRV   100
101   GGVQSLGGTG   ALRIGAEFLA   RWYNGTNNKD   TPVYVSSPTW   ENHNGVFTTA   150
151   GFKDIRSYRY   WDTEKRGLDL   QGFLSDLENA   PEFSIFVLHA   CAHNPTGTDP   200
201   TPEQWKQIAS   VMKRRFLFPF   FDSAYQGFAS   GNLEKDAWAI   RYFVSEGFEL   250
251   FCAQSFSKNF   GLYNERVGNL   TVVAKEPDSI   LRVLSQMQKI   VRVTWSNPPA   300
301   QGARIVARTL   SDPELFHEWT   GNVKTMADRI   LSMRSELRAR   LEALKTPGTW   350
351   NHITDQIGMF   SFTGLNPKQV   EYLINQKHIY   LLPSGRINMC   GLTTKNLDYV   400
401   ATSIHEAVTK   IQ         450

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
43_ASP GLY gnomAD
chr10:101180550 		rs145279669
- 0.000111542 -
43_ASP GLY 8.3kJPN
chr10:101180550 		rs145279669
- 0.0012 -
59_LYS ASN gnomAD
chr10:101180501 		rs201941343
- 0.000103423 -
84_SER PHE 8.3kJPN
chr10:101180427 		-
- 0.0001 -
85_ARG HIS gnomAD
chr10:101180424 		rs146802616
- 0.00023089 -
87_ALA VAL 8.3kJPN
chr10:101180418 		-
- 0.0001 -
132_PRO THR 8.3kJPN
chr10:101166510 		rs749267346
- 0.0001 -
144_ASN ASP 8.3kJPN
chr10:101165998 		-
- 0.0001 -
157_SER CYS 8.3kJPN
chr10:101165958 		-
- 0.0001 -
159_ARG HIS gnomAD
chr10:101165952 		rs146049867
- 0.00070808 -
175_ASN HIS 8.3kJPN
chr10:101165905 		rs771708711
- 0.0008 -
182_GLU GLY gnomAD
chr10:101165607 		rs142860219
- 0.00244155 -
182_GLU GLY 8.3kJPN
chr10:101165607 		rs142860219
- 0.0015 -
202_PRO LEU 8.3kJPN
chr10:101165547 		rs753858876
- 0.0001 -
207_GLN GLU gnomAD
chr10:101165533 		rs374966349
- 0.00018307 -
215_ARG TRP 8.3kJPN
chr10:101163628 		rs774097877
- 0.0001 -
252_CYS ARG 8.3kJPN
chr10:101163517 		-
- 0.0001 -
258_LYS ASN 8.3kJPN
chr10:101163497 		-
- 0.0002 -
304_ARG GLN 8.3kJPN
chr10:101163271 		rs769200718
- 0.0001 -
352_HIS ASP 8.3kJPN
chr10:101162382 		-
- 0.0001 -
363_THR SER 8.3kJPN
chr10:101162348 		-
- 0.0001 -
369_GLN GLU gnomAD
chr10:101157438 		rs76850691
- 0.00518302 -
369_GLN GLU 8.3kJPN
chr10:101157438 		rs76850691
- 0.013 -
386_ARG GLN 8.3kJPN
chr10:101157386 		-
- 0.0001 -
389_VAL MET 8.3kJPN
chr10:101157378 		rs769642084
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.