PDB ID 1AO6 CHAIN A
Protein name SERUM ALBUMIN
Uniprot Accession P02768
The number of similar proteins 106
The number of binding states 8
The number of binding partners 7
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1AO6 (CHAIN: A)
1 Monomeric state
2 P02768  
3 4HGK  
4 5VNW  
5 2VDB  
6 P61769   P55899  
7 5FUO   5FUO  
8 P02768   P02768  
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partners
  2
  1
  0
Sequence information
1   DAHKSEVAHR   FKDLGEENFK   ALVLIAFAQY   LQQCPFEDHV   KLVNEVTEFA   50
51   KTCVADESAE   NCDKSLHTLF   GDKLCTVATL   RETYGEMADC   CAKQEPERNE   100
101   CFLQHKDDNP   NLPRLVRPEV   DVMCTAFHDN   EETFLKKYLY   EIARRHPYFY   150
151   APELLFFAKR   YKAAFTECCQ   AADKAACLLP   KLDELRDEGK   ASSAKQRLKC   200
201   ASLQKFGERA   FKAWAVARLS   QRFPKAEFAE   VSKLVTDLTK   VHTECCHGDL   250
251   LECADDRADL   AKYICENQDS   ISSKLKECCE   KPLLEKSHCI   AEVENDEMPA   300
301   DLPSLAADFV   ESKDVCKNYA   EAKDVFLGMF   LYEYARRHPD   YSVVLLLRLA   350
351   KTYETTLEKC   CAAADPHECY   AKVFDEFKPL   VEEPQNLIKQ   NCELFEQLGE   400
401   YKFQNALLVR   YTKKVPQVST   PTLVEVSRNL   GKVGSKCCKH   PEAKRMPCAE   450
451   DYLSVVLNQL   CVLHEKTPVS   DRVTKCCTES   LVNRRPCFSA   LEVDETYVPK   500
501   EFNAETFTFH   ADICTLSEKE   RQIKKQTALV   ELVKHKPKAT   KEQLKAVMDD   550
551   FAAFVEKCCK   ADDKETCFAE   EGKKLVAASQ   AALGL     600
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
49_PHE TYR VAR_010657 - Polymorphism -
60_GLU LYS VAR_000507 rs77050410 Polymorphism -
63_ASP ASN VAR_000508 rs78574148 Polymorphism -
66_LEU PRO VAR_013011 rs77892378 Disease Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]
82_GLU LYS VAR_000509 rs80296402 Polymorphism -
97_GLU GLY VAR_014290 - Polymorphism -
114_ARG TER ClinVar
chr4:74274452
rs77238412 Pathogenic Analbuminemia [MedGen:C0878666,OMIM:616000,Orphanet:ORPHA86816]
114_ARG GLY VAR_000510 rs77238412 Polymorphism -
119_GLU LYS VAR_000511 rs75522063 Polymorphism -
122_VAL GLU VAR_013012 rs77752336 Polymorphism -
128_HIS ARG VAR_000512 rs80095457 Polymorphism -
177_CYS PHE VAR_000513 rs77656691 Polymorphism -
191_ALA THR VAR_014291 rs3210154 Polymorphism -
191_ALA VAL VAR_014292 rs3204504 Polymorphism -
196_GLN LEU VAR_014293 rs3210163 Polymorphism -
218_ARG HIS VAR_000514 rs75002628 Disease Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]
218_ARG PRO VAR_013013 rs75002628 Disease Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]
225_LYS GLN VAR_000515 rs79804069 Polymorphism -
240_LYS GLU VAR_000516 rs79377490 Polymorphism -
268_GLN ARG VAR_000517 rs80002911 Polymorphism -
269_ASP GLY VAR_000518 rs79744198 Polymorphism -
276_LYS ASN VAR_000519 rs74718349 Polymorphism -
313_LYS ASN VAR_000520 rs72552710 Polymorphism -
314_ASP GLY VAR_013014 rs76242087 Polymorphism -
314_ASP VAL VAR_013015 rs76242087 Polymorphism -
318_ASN LYS VAR_000521 rs77544362 Polymorphism -
320_ALA THR VAR_000522 rs78953271 Polymorphism -
321_GLU LYS VAR_000523 rs72552711 Polymorphism -
333_GLU LYS VAR_000524 rs77354753 Polymorphism -
354_GLU LYS VAR_000525 rs76593094 Polymorphism -
358_GLU LYS VAR_000526 rs75791663 Polymorphism -
359_LYS ASN VAR_013016 rs75069738 Polymorphism -
365_ASP HIS VAR_000527 rs77187142 Polymorphism -
365_ASP VAL VAR_000528 rs78538497 Polymorphism -
372_LYS GLU VAR_000529 rs78166690 Polymorphism -
375_ASP ASN VAR_000530 rs77514449 Polymorphism -
376_GLU LYS VAR_000531 rs79047363 Polymorphism -
376_GLU GLN VAR_000532 rs79047363 Polymorphism -
382_GLU LYS VAR_000533 rs76483862 Polymorphism -
396_GLU LYS VAR_014294 - Polymorphism -
410_ARG CYS VAR_013017 rs78575701 Polymorphism -
466_LYS GLU VAR_014295 rs1063469 Polymorphism -
479_GLU LYS VAR_000534 rs80259813 Polymorphism -
494_ASP ASN VAR_000535 rs75920790 Polymorphism -
501_GLU LYS VAR_000536 rs75523493 Polymorphism -
505_GLU LYS VAR_000537 rs74826639 Polymorphism -
533_VAL MET VAR_013018 rs78284052 Polymorphism -
536_LYS GLU VAR_000538 rs77645174 Polymorphism -
541_LYS GLU VAR_000539 rs80345158 Polymorphism -
550_ASP GLY VAR_000540 rs79738788 Polymorphism -
550_ASP ALA VAR_000541 rs79738788 Polymorphism -
560_LYS GLU VAR_013019 rs76671808 Polymorphism -
563_ASP ASN VAR_000542 rs76587671 Polymorphism -
565_GLU LYS VAR_000543 rs75709682 Polymorphism -
570_GLU LYS ClinVar
chr4:74285351
rs79228041 Pathogenic ALBUMIN B [na]
573_LYS GLU VAR_000545 rs80106970 Polymorphism -
574_LYS ASN VAR_000546 rs75738598 Polymorphism -