PDB ID 1APM CHAIN E
Protein name cAMP-DEPENDENT PROTEIN KINASE
Uniprot Accession P05132
The number of similar proteins 281
The number of binding states 7
The number of binding partners 4
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1APM (CHAIN: E)
1 Monomeric state
2 P12367  
3 P12369  
4 P05132  
5 P42588  
6 P31324   P31324  
7 P00517   P00517  

P00517  
Downdload
 Format:  
Molecule viewer
#binding
partners
  3
  2
  1
  0
Sequence information
1   GNAAAAKKGX   EQESVKEFLA   KAKEDFLKKW   ETPSQNTAQL   DQFDRIKTLG   50
51   TGSFGRVMLV   KHKESGNHYA   MKILDKQKVV   KLKQIEHTLN   EKRILQAVNF   100
101   PFLVKLEFSF   KDNSNLYMVM   EYVAGGEMFS   HLRRIGRFAE   PHARFYAAQI   150
151   VLTFEYLHSL   DLIYRDLKPE   NLLIDQQGYI   QVTDFGFAKR   VKGRTWXLCG   200
201   TPEYLAPEII   LSKGYNKAVD   WWALGVLIYE   MAAGYPPFFA   DQPIQIYEKI   250
251   VSGKVRFPSH   FSSDLKDLLR   NLLQVDLTKR   FGNLKNGVND   IKNHKWFATT   300
301   DWIAIYQRKV   EAPFIPKFKG   PGDTSNFDDY   EEEEIRVXIN   EKCGKEFTEF   350
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
73_ILE MET ClinVar
chr9:71628787
rs724159972 Pathogenic Platelet-type bleeding disorder 19 [MedGen:C4015405,OMIM:616176,Orphanet:ORPHA438207]
205_LEU ARG ClinVar
chr19:14208416
rs386352352 Pathogenic/Likely pathogenic Pigmented nodular adrenocortical disease, primary, 4 [MedGen:C4014425,OMIM:615830]; not provided [MedGen:CN517202]