PDB ID 1B50     CHAIN A
Protein name MIP-1A
Uniprot Accession P10147
The number of similar proteins 23
The number of binding states 8
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1B50 (CHAIN: A)
1 P10147  
2 Monomeric state
3 Q2F862  
4 P14735  
5 P0C8E7  
6 P10147   P10147  
7 P10147   P10147   P10147  
8 P10147   P10147   P10147   P10147  

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Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   SLAADTPTAC   CFSYTSRQIP   QNFIAAYFET   SSQCSKPGVI   FLTKRSRQVC   50
51   ADPSEEWVQK   YVSDLELSA         100

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
2_LEU PRO 8.3kJPN
chr17:34523311 		-
- 0.0001 -
2_LEU PHE 8.3kJPN
chr17:34523997 		rs1156645499
- 0.0001 -
7_PRO LEU gnomAD
chr17:34523296 		rs1225681584
- 0.000105252 -
8_THR ASN 8.3kJPN
chr17:34523293 		-
- 0.0005 -
9_ALA THR 8.3kJPN
chr17:34624865 		rs1365254271
- 0.0001 -
12_PHE CYS 8.3kJPN
chr17:34523281 		-
- 0.0003 -
12_PHE CYS 8.3kJPN
chr17:34624855 		-
- 0.0004 -
13_SER ARG 8.3kJPN
chr17:34624851 		-
- 0.0001 -
17_ARG TRP 8.3kJPN
chr17:34416599 		rs764705131
- 0.0001 -
17_ARG TER 8.3kJPN
chr17:34624841 		-
- 0.0001 -
21_GLN ARG 8.3kJPN
chr17:34624828 		-
- 0.0001 -
24_ILE THR gnomAD
chr17:34416577 		rs146554516
- 0.000346087 -
27_TYR HIS 8.3kJPN
chr17:34416569 		-
- 0.0001 -
29_GLU LYS 8.3kJPN
chr17:34416563 		-
- 0.0001 -
34_CYS TYR 8.3kJPN
chr17:34523215 		-
- 0.0001 -
38_GLY SER gnomAD
chr17:34416536 		rs1130374
- 0.000895679 -
38_SER GLY gnomAD
chr17:34624778 		rs1445208817
- 0.000135648 -
38_GLY SER 8.3kJPN
chr17:34416536 		rs1130374
- 0.0001 -
38_SER GLY 8.3kJPN
chr17:34523204 		rs1166153732
- 0.0012 -
38_SER GLY 8.3kJPN
chr17:34624778 		rs1445208817
- 0.001 -
41_PHE LEU 8.3kJPN
chr17:34624348 		rs1422042799
- 0.0005 -
44_LYS ARG 8.3kJPN
chr17:34624338 		-
- 0.0001 -
46_SER GLY gnomAD
chr17:34416092 		rs5029408
- 0.000159251 -
46_SER GLY 8.3kJPN
chr17:34416092 		rs5029408
- 0.0004 -
47_ARG GLN gnomAD
chr17:34624329 		rs757433231
- 0.000128167 -
47_ARG GLN 8.3kJPN
chr17:34416088 		rs748914581
- 0.0001 -
55_GLU ASP VAR_048701 rs34171309
LB/B - -
55_GLU ASP gnomAD
chr17:34416063 		rs34171309
- 0.00808102 -
60_LYS ARG 8.3kJPN
chr17:34416049 		rs548448001
- 0.0001 -
62_VAL ILE 8.3kJPN
chr17:34522711 		rs1473476410
- 0.0005 -
64_ASP ASN gnomAD
chr17:34416038 		rs141182065
- 0.00175559 -
64_ASP ASN 8.3kJPN
chr17:34416038 		rs141182065
- 0.0001 -
67_LEU PRO gnomAD
chr17:34522695 		rs201343647
- 0.000166099 -
67_LEU PRO 8.3kJPN
chr17:34416028 		rs532580689
- 0.0001 -
67_LEU PRO 8.3kJPN
chr17:34522695 		rs201343647
- 0.3199 -
67_LEU PRO 8.3kJPN
chr17:34624269 		rs759908045
- 0.0176 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.