PiSITE

PDB ID	1BCC	CHAIN	F
Protein name	UBIQUINOL CYTOCHROME C OXIDOREDUCTASE
Uniprot Accession	P00129
The number of similar proteins	39
The number of binding states	3
The number of binding partners	5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding state	Binding partners
	1BCC (CHAIN: F)
1	2BCC 2BCC P18946
2	Monomeric state
3	P13271 P00125 P00157 P23004 P31800

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Molecule viewer

Only interaction residues

#binding
partners

	2
	1
	0

Sequence information

1

AGRPAVSASS

RWLEGIRKWY

YNAAGFNKYG

LMRDDTIYEN

DDVKEAIRRL

50

51

PENLYDDRMF

RIKRALDLNM

RQQILPKEQW

TKYEEDVPYL

EPYLKEVIRE

100

101

RKEREEWDK

150

Variants

	Residue	AA	Source	dbSNP	Clinical Significance	Allele Frequency (> 0.0001)	Disease name
	18_LYS	ILE	ClinVar chr8:97245419	rs863224257	Likely pathogenic	-	not provided [MedGen:CN517202]
	59_MET	LEU	gnomAD chr8:97244082	rs145974195	-	0.000230703	-
	66_LEU	GLN	gnomAD chr8:97244060	rs139283183	-	0.00127275	-
	73_GLN	LEU	8.3kJPN chr8:97244039	-	-	0.0001	-
	74_ILE	VAL	8.3kJPN chr8:97244037	-	-	0.0001	-
	82_LYS	ASN	gnomAD chr8:97244011	rs145828292	-	0.000155149	-
	99_ARG	GLN	8.3kJPN chr8:97243320	rs746768081	-	0.0001	-
	103_GLU	TER	ClinVar chr8:97243309	rs1554577679	Likely pathogenic	-	not provided [MedGen:C3661900]
	108_ALA	THR	8.3kJPN chr8:97243294	-	-	0.0001	-

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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364