PDB ID 1CVF CHAIN A
Protein name CARBONIC ANHYDRASE II
Uniprot Accession P00918
The number of similar proteins 740
The number of binding states 3
The number of binding partners 2
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1CVF (CHAIN: A)
1 Monomeric state
2 1G6V  
3 P00918  
Downdload
 Format:  
Molecule viewer
#binding
partners
  2
  1
  0
Sequence information
1   SHHWGYGKHN   GPEHWHKDFP   IAKGERQSPV   DIDTHTAKYD   PSLKPLSVSY   50
51   DQATSLRILN   NGHAFNVEFD   DSQDKAVLKG   GPLDGTYRLI   QFAFHWGSLD   100
101   GQGSEHTVDK   KKYAAELHLV   HWNTKYGDFG   KAVQQPDGLA   VLGIFLKVGS   150
151   AKPGLQKVVD   VLDSIKTKGK   SADFTNFDPR   GLLPESLDYW   TYPGSLTTPP   200
201   LLECVTWIVL   KEPISVSSEQ   VLKFRKLNFN   GEGEPEELMV   DNWRPAQPLK   250
251   NRQIKASFK           300
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
7_TYR TER ClinVar
chr8:86376331
rs1554709677 Pathogenic Osteopetrosis with renal tubular acidosis [MedGen:C0345407,OMIM:259730,SNOMED CT:254122007]
18_LYS GLU ClinVar
chr8:86377518
rs118203931 Pathogenic CARBONIC ANHYDRASE II VARIANT [na]
40_TYR TER ClinVar
chr8:86377586
rs118203934 Pathogenic Osteopetrosis with renal tubular acidosis [MedGen:C0345407,OMIM:259730,SNOMED CT:254122007]
92_GLN PRO VAR_001381 rs1304160279 Disease Osteopetrosis, autosomal recessive 3 (OPTB3) [MIM:259730]
107_HIS TYR ClinVar
chr8:86386008
rs118203933 Pathogenic Osteopetrosis with renal tubular acidosis [MedGen:C0345407,OMIM:259730,SNOMED CT:254122007]
145_GLY ARG VAR_021010 - Disease Osteopetrosis, autosomal recessive 3 (OPTB3) [MIM:259730]
237_PRO HIS ClinVar
chr8:86392942
rs118203932 Pathogenic CARBONIC ANHYDRASE II VARIANT [na]
253_ASN ASP VAR_001384 rs2228063 Polymorphism -