PDB ID 1CY2     CHAIN A
Protein name DNA TOPOISOMERASE I
Uniprot Accession P06612
The number of similar proteins 12
The number of binding states 1
The number of binding partners 0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1CY2 (CHAIN: A)
1 Monomeric state

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  0

Sequence information

1   GSMGKALVIV   ESPAKAKTIN   KYLGSDYVVK   SSVGHIRDLP   TSGSAAKKSA   50
51   DSTSTKTAKK   PKKDERGALV   NRMGVDPWHN   WEAHYEVLPG   KEKVVSELKQ   100
101   LAEKADHIYL   ATDLDREGEA   IAWHLREVIG   GDDARYSRVV   FNEITKNAIR   150
151   QAFNKPGELN   IDRVNAQQAR   RFMDRVVGYM   VSPLLWKKIA   RGLSAGRVQS   200
201   VAVRLVVERE   REIKAFVPEE   FWEVDASTTT   PSGEALALQV   THQNDKPFRP   250
251   VNKEQTQAAV   SLLEKARYSV   LEREDKPTTS   KPGAPFITST   LQQAASTRLG   300
301   FGVKKTMMMA   QRLYEAGYIT   YMRTDSTNLS   QDAVNMVRGY   ISDNFGKKYL   350
351   PESPNQYASK   ENSQEAHEAI   RPSDVNVMAE   SLKDMEADAQ   KLYQLIWRQF   400
401   VACQMTPAKY   DSTTLTVGAG   DFRLKARGRI   LRFDGWTKVM   PALRKGDEDR   450
451   ILPAVNKGDA   LTLVELTPAQ   HFTKPPARFS   EASLVKELEK   RGIGRPSTYA   500
501   SIISTIQDRG   YVRVENRRFY   AEKMGEIVTD   RLEENFRELM   NYDFTAQMEN   550
551   SLDQVANHEA   EWKAVLDHFF   SDFTQQLDKA   EKDPEEGGMR   PNQMVLTSI   600

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

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