PDB ID 1EEM     CHAIN A
Protein name GLUTATHIONE-S-TRANSFERASE
Uniprot Accession P78417
The number of similar proteins 21
The number of binding states 2
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1EEM (CHAIN: A)
1 Monomeric state
2 P78417  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   MSGESARSLG   KGSAPPGPVP   EGSIRIYSMR   FCPFAERTRL   VLKAKGIRHE   50
51   VININLKNKP   EWFFKKNPFG   LVPVLENSQG   QLIYESAITC   EYLDEAYPGK   100
101   KLLPDDPYEK   ACQKMILELF   SKVPSLVGSF   IRSQNKEDYA   GLKEEFRKEF   150
151   TKLEEVLTNK   KTTFFGGNSI   SMIDYLIWPW   FERLEAMKLN   ECVDHTPKLK   200
201   LWMAAMKEDP   TVSALLTSEK   DWQGFLELYL   QNSPEACDYG   L   250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
7_ARG LYS gnomAD
chr10:106014706 		rs72559704
- 0.00221661 -
7_ARG GLY 8.3kJPN
chr10:106014705 		-
- 0.0001 -
14_ALA THR 8.3kJPN
chr10:106014926 		-
- 0.0001 -
26_ILE THR 8.3kJPN
chr10:106014963 		-
- 0.0001 -
32_CYS TYR VAR_061231 rs45529437
LB/B - -
32_CYS TYR gnomAD
chr10:106014981 		rs45529437
- 0.000322591 -
40_LEU ARG 8.3kJPN
chr10:106015005 		-
- 0.0001 -
46_GLY ARG 8.3kJPN
chr10:106015022 		-
- 0.0001 -
56_LEU VAL 8.3kJPN
chr10:106019356 		-
- 0.0001 -
86_SER CYS VAR_029269 rs11509436
LB/B - -
107_PRO SER 8.3kJPN
chr10:106019509 		rs150506133
- 0.0002 -
140_ALA ASP VAR_016811 rs4925
LB/B - -
140_ALA ASP gnomAD
chr10:106022789 		rs4925
- 0.247701 -
140_ALA ASP 8.3kJPN
chr10:106022789 		rs4925
- 0.1166 -
141_GLY ASP 8.3kJPN
chr10:106022792 		-
- 0.0001 -
147_ARG CYS 8.3kJPN
chr10:106022809 		rs777056461
- 0.0002 -
147_ARG HIS 8.3kJPN
chr10:106022810 		rs141387929
- 0.0001 -
163_THR ILE gnomAD
chr10:106025864 		rs116993524
- 0.00200509 -
168_ASN SER gnomAD
chr10:106025879 		rs148403642
- 0.000640454 -
172_MET VAL 8.3kJPN
chr10:106025890 		-
- 0.0001 -
179_PRO LEU gnomAD
chr10:106025912 		rs201522765
- 0.000767792 -
179_PRO LEU 8.3kJPN
chr10:106025912 		rs201522765
- 0.0026 -
183_ARG GLN 8.3kJPN
chr10:106025924 		rs1292504288
- 0.0001 -
208_GLU LYS VAR_024484 rs11509438
LB/B - -
208_GLU LYS gnomAD
chr10:106027059 		rs11509438
- 0.0368204 -
208_GLU LYS 8.3kJPN
chr10:106027059 		rs11509438
- 0.0059 -
236_ALA VAL VAR_026583 rs11509439
LB/B - -
236_ALA VAL gnomAD
chr10:106027144 		rs11509439
- 0.00510689 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.