PDB ID 1EQF CHAIN A
Protein name RNA POLYMERASE II TRANSCRIPTION INITIATION FACTOR
Uniprot Accession P21675
The number of similar proteins 4
The number of binding states 2
The number of binding partners 1
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1EQF (CHAIN: A)
1 Monomeric state
2 Q9Y294   Q9Y294  
Downdload
 Format:  
Molecule viewer
#binding
partners
  1
  0
Sequence information
1   GTTVHCDYLN   RPHKSIHRRR   TDPMVTLSSI   LESIINDMRD   LPNTYPFHTP   50
51   VNAKVVKDYY   KIITRPMDLQ   TLRENVRKRL   YPSREEFREH   LELIVKNSAT   100
101   YNGPKHSLTQ   ISQSMLDLCD   EKLKEKEDKL   ARLEKAINPL   LDDDDQVAFS   150
151   FILDNIVTQK   MMAVPDSWPF   HHPVNKKFVP   DYYKVIVNPM   DLETIRKNIS   200
201   KHKYQSRESF   LDDVNLILAN   SVKYNGPESQ   YTKTAQEIVN   VCYQTLTEYD   250
251   EHLTQLEKDI   CTAKEAALEE   AELESLDPMT       300
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
1383_VAL ILE VAR_048433 rs7050748 Polymorphism -
1408_PRO LEU ClinVar
chrX:70627843
rs1555980523 Likely pathogenic Mental retardation, X-linked, syndromic 33 [MedGen:C4225418,OMIM:300966]
1431_ARG HIS VAR_076399 - Unclassified Mental retardation, X-linked, syndromic, 33 (MRXS33) [MIM:300966]
1438_LEU PRO ClinVar
chrX:70627933
rs1555980614 Likely pathogenic not provided [MedGen:CN517202]
1464_HIS ARG ClinVar
chrX:70641168
rs1064793874 Likely pathogenic not provided [MedGen:CN517202]
1496_ASN HIS VAR_076400 - Unclassified Mental retardation, X-linked, syndromic, 33 (MRXS33) [MIM:300966]