PDB ID 1F3L     CHAIN A
Protein name PROTEIN ARGININE METHYLTRANSFERASE PRMT3
Uniprot Accession O70467
The number of similar proteins 8
The number of binding states 1
The number of binding partners 0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1F3L (CHAIN: A)
1 Monomeric state

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  0

Sequence information

1   DLQEDEDGVY   FSSYGHYGIH   EEMLKDKVRT   ESYRDFIYQN   PHIFKDKVVL   50
51   DVGCGTGILS   MFAAKAGAKK   VIAVDQSEIL   YQAMDIIRLN   KLEDTIVLIK   100
101   GKIEEVSLPV   EKVDVIISEW   MGYFLLFESM   LDSVLYAKSK   YLAKGGSVYP   150
151   DICTISLVAV   SDVSKHADRI   AFWDDVYGFN   MSCMKKAVIP   EAVVEVVDHK   200
201   TLISDPCDIK   HIDCHTTSIS   DLEFSSDFTL   RTTKTAMCTA   VAGYFDIYFE   250
251   KNCHNRVVFS   TGPQSTKTHW   KQTIFLLEKP   FPVKAGEALK   GKITVHKNKK   300
301   DPRSLIVTLT   LNSSTQTYSL   Q       350

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
241_ARG TER 8.3kJPN
chr11:20424489 		rs138697834
- 0.0002 -
249_HIS ARG 8.3kJPN
chr11:20424514 		rs772006874
- 0.0006 -
251_PHE LEU gnomAD
chr11:20424519 		rs149362244
- 0.000394099 -
268_MET LEU 8.3kJPN
chr11:20429496 		rs201331276
- 0.0001 -
291_MET ILE 8.3kJPN
chr11:20429567 		-
- 0.0001 -
293_ILE VAL 8.3kJPN
chr11:20429571 		-
- 0.0001 -
294_ILE LEU gnomAD
chr11:20429574 		rs144295044
- 0.000841716 -
337_MET VAL 8.3kJPN
chr11:20473700 		rs142211701
- 0.0001 -
343_TYR HIS gnomAD
chr11:20473718 		rs139028225
- 0.000334563 -
362_ILE VAL 8.3kJPN
chr11:20483546 		rs753879970
- 0.0001 -
396_ILE THR gnomAD
chr11:20483649 		rs201657855
- 0.00014722 -
400_VAL ILE gnomAD
chr11:20483660 		rs775743161
- 0.000386008 -
413_PRO ARG gnomAD
chr11:20483700 		rs199892546
- 0.000255892 -
437_LEU VAL gnomAD
chr11:20486063 		rs3758805
- 0.00639813 -
437_LEU VAL 8.3kJPN
chr11:20486063 		rs3758805
- 0.0812 -
465_VAL MET 8.3kJPN
chr11:20515716 		rs148386517
- 0.0001 -
505_SER ASN gnomAD
chr11:20529886 		rs6483700
- 0.996732 -
506_LYS ARG gnomAD
chr11:20529889 		rs563022985
- 0.000410476 -
507_LYS ARG gnomAD
chr11:20529892 		rs74772442
- 0.0143091 -
514_VAL ALA 8.3kJPN
chr11:20529913 		rs767615798
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.