PDB ID 1MEN     CHAIN A
Protein name Phosphoribosylglycinamide formyltransferase
Uniprot Accession P22102
The number of similar proteins 38
The number of binding states 1
The number of binding partners 0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1MEN (CHAIN: A)
1 Monomeric state

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  0

Sequence information

1   ASMTGGQQMG   RILVAVLISG   TGSNLQALID   STREPNSSAQ   IDIVISNKAA   50
51   VAGLDKAERA   GIPTRVINHK   LYKNRVEFDS   AIDLVLEEFS   IDIVCLAGFM   100
101   RILSGPFVQK   WNGKMLNIHP   SLLPSFKGSN   AHEQALETGV   TVTGCTVHFV   150
151   AEDVDAGQII   LQEAVPVKRG   DTVATLSERV   KLAEHKIFPA   ALQLVASGTV   200
201   QLGENGKICW   VKEEPLEHHH   HHH       250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
24_PRO SER gnomAD
chr21:34878373 		rs560269221
- 0.000143165 -
33_VAL ILE 8.3kJPN
chr21:34878346 		-
- 0.0001 -
63_ASN SER gnomAD
chr21:34877984 		rs527760350
- 0.000163319 -
63_ASN SER 8.3kJPN
chr21:34877984 		rs527760350
- 0.0005 -
72_ASP ASN gnomAD
chr21:34877958 		rs138428594
- 0.000124012 -
99_LYS ARG 8.3kJPN
chr21:34877876 		-
- 0.0001 -
162_VAL ILE 8.3kJPN
chr21:34876559 		-
- 0.0001 -
163_ALA THR 8.3kJPN
chr21:34876556 		rs781248889
- 0.0001 -
164_THR ALA 8.3kJPN
chr21:34876553 		rs755290317
- 0.0001 -
167_GLU LYS gnomAD
chr21:34876544 		rs369961402
- 0.00039789 -
169_VAL ILE gnomAD
chr21:34876538 		rs9636610
- 0.000923082 -
169_VAL ILE 8.3kJPN
chr21:34876538 		rs9636610
- 0.0032 -
171_LEU VAL 8.3kJPN
chr21:34876532 		-
- 0.0004 -
177_PHE LEU 8.3kJPN
chr21:34876514 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.