PDB ID 1SZ7     CHAIN A
Protein name Trafficking protein particle complex subunit 3
Uniprot Accession O43617
The number of similar proteins 10
The number of binding states 5
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1SZ7 (CHAIN: A)
1 Monomeric state
2 Q86SZ2  
3 Q6DGL5  
4 Q6DGL5   2J3W  
5 Q9Y296   Q5NCF2   O75865  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   MSHHHHHHGS   SRQANRGTES   KKMSSELFTL   TYGALVTQLC   KDYENDEDVN   50
51   KQLDKMGFNI   GVRLIEDFLA   RSNVGRCHDF   RETADVIAKV   AFKMYLGITP   100
101   SITNWSPAGD   EFSLILENNP   LVDFVELPDN   HSSLIYSNLL   CGVLRGALEM   150
151   VQMAVEAKFV   QDTLKGDGVT   EIRMRFIRRI   EDNLPAGEEA   AAWSHPQFEK   200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
62_ARG TRP ClinVar
chr1:36605377 		rs751375244
Likely pathogenic - Bardet-Biedl syndrome [MONDO:MONDO:0015229,MedGen:C0752166,OMIM:PS209900,Orphanet:110]
62_ARG PRO 8.3kJPN
chr1:36605376 		-
- 0.0001 -
76_ASP GLY 8.3kJPN
chr1:36605334 		-
- 0.0001 -
92_SER GLY gnomAD
chr1:36603546 		rs138894050
- 0.0002387 -
129_ASN SER 8.3kJPN
chr1:36603434 		rs758862062
- 0.0001 -
131_LEU PHE gnomAD
chr1:36603427 		rs141225393
- 0.000175 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.