PDB ID 1U0N CHAIN D
Protein name Platelet glycoprotein Ib
Uniprot Accession P07359
The number of similar proteins 13
The number of binding states 5
The number of binding partners 3
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1U0N (CHAIN: D)
1 P22030   P04275  
2 Monomeric state
3 P04275  
4 P00734  
5 P00734   P00734  
Downdload
 Format:  
Molecule viewer
#binding
partners
  2
  1
  0
Sequence information
1   HPICEVSKVA   SHLEVNCDKR   QLTALPPDLP   KDTTILHLSE   NLLYTFSLAT   50
51   LMPYTRLTQL   NLDRCELTKL   QVDGTLPVLG   TLDLSHNQLQ   SLPLLGQTLP   100
101   ALTVLDVSFN   RLTSLPLGAL   RGLGELQELY   LKGNELKTLP   PGLLTPTPKL   150
151   EKLSLANNQL   TELPAGLLNG   LENLDTLLLQ   ENSLYTIPKG   FFGSHLLPFA   200
201   FLHGNPWLCN   CEILYFRRWL   QDNAENVYVW   KQGVDVKAMT   SNVASVQCDN   250
251   SDKFPVYKYP   GKGCP         300
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
56_ARG HIS VAR_011909 rs6068 Polymorphism -
57_LEU PHE ClinVar
chr17:4836116
rs121908063 Pathogenic Bernard-Soulier syndrome, type A2, autosomal dominant [MedGen:C3277076,OMIM:153670]
65_CYS ARG VAR_005256 rs781541857 Disease Bernard-Soulier syndrome (BSS) [MIM:231200]
70_LEU PHE VAR_013511 rs13306411 Polymorphism -
129_LEU PRO VAR_014207 rs771048666 Disease Bernard-Soulier syndrome (BSS) [MIM:231200]
145_THR MET VAR_005257 rs6065 Polymorphism -
156_ALA VAL ClinVar
chr17:4836414
rs121908065 Pathogenic Bernard-Soulier syndrome, type A1 [MedGen:C3278148]; Bernard-Soulier syndrome, type A2, autosomal dominant [MedGen:C3277076,OMIM:153670]
180_GLN TER ClinVar
chr17:4836485
rs371226354 Likely pathogenic not provided [MedGen:CN517202]
209_CYS SER ClinVar
chr17:4836572
rs1394634674 Pathogenic Bernard-Soulier syndrome, type A1 [MedGen:C3278148]
233_GLY VAL ClinVar
chr17:4836645
rs121908062 Pathogenic Pseudo von Willebrand disease [MedGen:C1280798,OMIM:177820,Orphanet:ORPHA52530,SNOMED CT:128115005]
233_GLY SER VAR_019657 - Disease Pseudo-von Willebrand disease (VWDP) [MIM:177820]
238_ALA SER VAR_011910 rs382524 Polymorphism -
239_MET VAL ClinVar
chr17:4836662
rs121908064 Pathogenic Pseudo von Willebrand disease [MedGen:C1280798,OMIM:177820,Orphanet:ORPHA52530,SNOMED CT:128115005]