PDB ID 1UEX CHAINC
Protein nameVON WILLEBRAND FACTOR
Uniprot Accession P04275
The number of similar proteins 9
The number of binding states 5
The number of binding partners 4
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1UEX (CHAIN: C)
1 2134244 2134245
2 Monomeric state
3 P07359
4 1890296 1890294
5 P22030 P22029 P07359
Downdload
Format:
Molecule viewer
#binding
partners
  4
  3
  2
  1
  0
Sequence information
1  EDISEPPLHD   FYCSRLLDLV   FLLDGSSRLS   EAEFEVLKAF   VVDMMERLRI   50
51  SQKWVRVAVV   EYHDGSHAYI   GLKDRKRPSE   LRRIASQVKY   AGSQVASTSE   100
101  VLKYTLFQIF   SKIDRPEASR   IALLLMASQE   PQRMSRNFVR   YVQGLKKKKV   150
151  IVIPVGIGPH   ANLKQIRLIE   KQAPENKAFV   LSSVDELEQQ   RDEIVSYLCD   200
201  LAPEAPPPT                                                    250
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
503_PRO LEU VAR_005791 rs61749370 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
505_HIS ASP VAR_005792 rs61749371 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
509_CYS PHE VAR_067340 rs63524161 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
543_ARG TRP VAR_005794 rs61749384 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
545_ARG CYS VAR_005795 rs61749387 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
550_TRP CYS VAR_005796 rs61749392 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
551_VAL LEU VAR_005797 rs61749393 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
553_VAL MET VAR_005798 rs61749397 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
555_VAL LEU VAR_005799 - Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
561_GLY SER VAR_005800 rs61749398 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
578_ARG GLN VAR_005801 rs61749403 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
611_ARG HIS VAR_005803 rs61750072 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
636_ARG HIS VAR_005805 rs216312 Polymorphism -
697_LEU VAL VAR_005806 rs61750088 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]
698_ALA VAL VAR_005807 rs61750089 Disease Von Willebrand disease 2 (VWD2) [MIM:613554]