PDB ID 2A8U CHAIN A
Protein name ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
Uniprot Accession P16442
The number of similar proteins 158
The number of binding states 2
The number of binding partners 1
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
2A8U (CHAIN: A)
1 Monomeric state
2 P16442  
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partners
  1
  0
Sequence information
1   FMVSLPRMVY   PQPKVLTPCR   KDVLVVTPWL   APIVWEGTFN   IDILNEQFRL   50
51   QNTTIGLTVF   AIKKYVAFLK   LFLETAEKHF   MVGHRVHYYV   FTDQPAAVPR   100
101   VTLGTGRQLS   VLEVGAYKRW   QDVSMRRMEM   ISDFCERRFL   SEVDYLVCVD   150
151   VDMEFRDHVG   VEILTPLFGT   LHPSFYGSSR   EAFTYERRPQ   SQAYIPKDEG   200
201   DFYYMGAFFG   GSVQEVQRLT   RACHQAMMVD   QANGIEAVWH   DESHLNKYLL   250
251   RHKPTKVLSP   EYLWDQQLLG   WPAVLRKLRF   TAVPKNHQAV   RNP   300
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
74_PRO SER VAR_019150 rs512770 Polymorphism -
156_PRO LEU VAR_003409 rs1053878 Polymorphism -
161_ARG HIS VAR_019151 rs8176738 Polymorphism -
163_THR MET VAR_036738 rs55756402 Polymorphism -
198_ARG TRP VAR_036739 - Polymorphism -
199_ARG CYS VAR_019152 rs8176739 Polymorphism -
214_MET ARG VAR_036740 - Polymorphism -
216_PHE ILE VAR_019153 rs8176740 Polymorphism -
223_GLU ASP VAR_036741 - Polymorphism -
230_GLY ARG VAR_055227 - Unclassified -
234_PRO ALA VAR_072628 - Polymorphism -
257_PRO LEU VAR_033540 rs8176745 Polymorphism -
277_VAL MET VAR_019154 rs8176748 Polymorphism -
288_MET ARG VAR_036742 - Polymorphism -
291_ASP ASN VAR_036743 - Polymorphism -