| PDB ID | 2BED
|
CHAIN | A |
|---|---|---|---|
| Protein name | Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit | ||
| Uniprot Accession | Q04631 | ||
| The number of similar proteins | 70 | ||
| The number of binding states | 2 | ||
| The number of binding partners | 2 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
Downdload
Molecule viewer
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Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source | dbSNP | Clinical Significance |
Allele Frequency (> 0.0001) |
Disease name | |
|---|---|---|---|---|---|---|---|
| 64_VAL | ILE |
gnomAD chr8:42911679 |
rs143321089
|
- | 0.00179624 | - | |
| 75_ILE | THR |
8.3kJPN chr8:42914258 |
rs779020919
|
- | 0.0005 | - | |
| 85_ASN | SER |
gnomAD chr8:42914288 |
rs151278515
|
- | 0.0015814 | - | |
| 85_ASN | ASP |
8.3kJPN chr8:42914287 |
-
|
- | 0.0001 | - | |
| 108_GLN | LEU |
8.3kJPN chr8:42919280 |
-
|
- | 0.0001 | - | |
| 117_PHE | LEU |
gnomAD chr8:42919308 |
rs138334666
|
- | 0.000266455 | - | |
| 121_ARG | TRP |
8.3kJPN chr8:42919318 |
rs745664729
|
- | 0.0001 | - | |
| 130_ASN | SER |
8.3kJPN chr8:42919346 |
rs768087218
|
- | 0.0001 | - | |
| 147_ASP | ASN |
8.3kJPN chr8:42924735 |
rs778274499
|
- | 0.0001 | - | |
| 184_GLN | ARG |
8.3kJPN chr8:42927368 |
rs201638101
|
- | 0.0016 | - | |
| 287_ARG | HIS |
gnomAD chr8:42939867 |
rs777603932
|
- | 0.000109658 | - | |
| 328_ASP | ASN |
gnomAD chr8:42939989 |
rs139144868
|
- | 0.000868512 | - | |
| 332_ASP | VAL |
8.3kJPN chr8:42940002 |
-
|
- | 0.0001 | - |