| PDB ID | 2CS2
|
CHAIN | A |
|---|---|---|---|
| Protein name | Poly [ADP-ribose] polymerase-1 | ||
| Uniprot Accession | P09874 | ||
| The number of similar proteins | 2 | ||
| The number of binding states | 1 | ||
| The number of binding partners | 0 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 2CS2 (CHAIN: A) | |
| 1 | Monomeric state |
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source | dbSNP | Clinical Significance |
Allele Frequency (> 0.0001) |
Disease name | |
|---|---|---|---|---|---|---|---|
| 19_ALA | VAL |
8.3kJPN chr1:226579961 |
rs1447203064
|
- | 0.0001 | - | |
| 24_LYS | ARG |
8.3kJPN chr1:226579946 |
rs758526385
|
- | 0.0002 | - | |
| 34_MET | THR |
8.3kJPN chr1:226579916 |
rs201841505
|
- | 0.0011 | - | |
| 42_VAL | LEU |
8.3kJPN chr1:226578319 |
-
|
- | 0.0001 | - | |
| 55_GLN | HIS |
gnomAD chr1:226578278 |
rs142376976
|
- | 0.000230813 | - | |
| 61_ARG | HIS |
8.3kJPN chr1:226578261 |
rs772993780
|
- | 0.0001 | - | |
| 78_ARG | GLN |
gnomAD chr1:226578210 |
rs200399922
|
- | 0.000155109 | - | |
| 78_ARG | GLN |
8.3kJPN chr1:226578210 |
rs200399922
|
- | 0.0001 | - | |
| 80_GLU | GLN |
8.3kJPN chr1:226578205 |
rs765820369
|
- | 0.0001 | - | |
| 88_GLY | ASP |
8.3kJPN chr1:226578180 |
-
|
- | 0.0001 | - | |
| 93_ALA | THR | VAR_014714 |
rs1805409
|
LB/B | - | - | |
| 93_ALA | THR |
gnomAD chr1:226578166 |
rs1805409
|
- | 0.00109367 | - | |
| 124_VAL | ALA |
gnomAD chr1:226576418 |
rs149927756
|
- | 0.000282475 | - | |
| 125_ALA | VAL |
gnomAD chr1:226576415 |
rs139232092
|
- | 0.000581002 | - | |
| 125_ALA | VAL |
8.3kJPN chr1:226576415 |
rs139232092
|
- | 0.0029 | - | |
| 126_LYS | ASN |
8.3kJPN chr1:226576411 |
-
|
- | 0.0001 | - |