PDB ID 2DMJ     CHAIN A
Protein name poly (ADP-ribose) polymerase family, member 1
GenBank ID 55663673
The number of similar proteins 9
The number of binding states 2
The number of binding partners 2

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2DMJ (CHAIN: A)
1 Monomeric state
2 P09874   P09874  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   GSSGSSGMAE   SSDKLYRVEY   AKSGRASCKK   CSESIPKDSL   RMAIMVQSPM   50
51   FDGKVPHWYH   FSCFWKVGHS   IRHPDVEVDG   FSELRWDDQQ   KVKKTAEAGG   100
101   SGPSSG           150

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
12_SER TRP gnomAD
chr1:226595617 		rs201256399
- 0.000193283 -
12_SER TRP 8.3kJPN
chr1:226595617 		rs201256399
- 0.0001 -
26_ALA THR 8.3kJPN
chr1:226595576 		-
- 0.0001 -
31_CYS ARG 8.3kJPN
chr1:226595561 		-
- 0.0001 -
35_ILE VAL 8.3kJPN
chr1:226595549 		-
- 0.0001 -
37_LYS ARG 8.3kJPN
chr1:226595542 		-
- 0.0001 -
61_PHE LEU 8.3kJPN
chr1:226590039 		rs3738708
- 0.0003 -
65_TRP ARG gnomAD
chr1:226590029 		rs370621373
- 0.000159271 -
82_SER PRO 8.3kJPN
chr1:226589978 		rs182219056
- 0.0009 -
85_ARG GLN 8.3kJPN
chr1:226589968 		rs139202063
- 0.0004 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.