PDB ID 2F3M     CHAIN A
Protein name Glutathione S-transferase Mu 1
Uniprot Accession P09488
The number of similar proteins 12
The number of binding states 1
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2F3M (CHAIN: A)
1 P09488  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   MPMILGYWDI   RGLAHAIRLL   LEYTDSSYEE   KKYTMGDAPD   YDRSQWLNEK   50
51   FKLGLDFPNL   PYLIDGAHKI   TQSNAILCYI   ARKHNLCGET   EEEKIRVDIL   100
101   ENQTMDNHMQ   LGMICYNPEF   EKLKPKYLEE   LPEKLKLYSE   FLGKRPWFAG   150
151   NKITFVDFLV   YDVLDLHRIF   EPKCLDAFPN   LKDFISRFEG   LEKISAYMKS   200
201   SRFLPRPVFS   KMAVWGNK         250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
0_MET ILE 8.3kJPN
chr1:110210740 		rs201905887
- 0.0049 -
2_MET VAL 8.3kJPN
chr1:110199018 		rs1282403867
- 0.0001 -
5_GLY ARG 8.3kJPN
chr1:110199027 		-
- 0.0001 -
8_ASP GLU gnomAD
chr1:110230522 		rs184653774
- 0.000136455 -
11_GLY ARG 8.3kJPN
chr1:110230529 		-
- 0.0004 -
13_ALA VAL 8.3kJPN
chr1:110255244 		-
- 0.0001 -
14_HIS GLN gnomAD
chr1:110230800 		rs567320393
- 0.000920852 -
15_ALA VAL gnomAD
chr1:110230802 		rs536289169
- 0.000482946 -
16_ILE MET gnomAD
chr1:110199348 		rs148886417
- 0.00112532 -
17_ARG LEU gnomAD
chr1:110199350 		rs138088784
- 0.000111343 -
17_ARG HIS gnomAD
chr1:110211063 		rs145910843
- 0.00136 -
25_SER TER 8.3kJPN
chr1:110211087 		-
- 0.0001 -
25_SER LEU 8.3kJPN
chr1:110255280 		-
- 0.0001 -
29_GLU LYS 8.3kJPN
chr1:110230843 		rs1259669984
- 0.0001 -
31_LYS TER 8.3kJPN
chr1:110211104 		rs556730458
- 0.0002 -
33_THR ALA gnomAD
chr1:110211110 		rs755629589
- 0.000115318 -
33_THR ALA 8.3kJPN
chr1:110211110 		rs755629589
- 0.0011 -
33_THR MET 8.3kJPN
chr1:110255304 		rs540779576
- 0.0002 -
39_ASP TYR 8.3kJPN
chr1:110211552 		-
- 0.0001 -
58_ASN SER 8.3kJPN
chr1:110211610 		rs371911407
- 0.0084 -
63_ILE MET gnomAD
chr1:110256120 		rs142675425
- 0.000425454 -
64_ASP ASN 8.3kJPN
chr1:110256121 		-
- 0.0001 -
66_THR ALA gnomAD
chr1:110211933 		rs2227960
- 0.00151891 -
66_ALA THR gnomAD
chr1:110256127 		rs17854972
- 0.0830589 -
66_ALA THR 8.3kJPN
chr1:110256127 		rs17854972
- 0.0002 -
76_LEU PRO 8.3kJPN
chr1:110256158 		rs1360731264
- 0.0001 -
77_CYS ARG gnomAD
chr1:110200266 		rs145858198
- 0.000107358 -
77_ARG CYS gnomAD
chr1:110256160 		rs147739570
- 0.000127244 -
77_CYS ARG 8.3kJPN
chr1:110200266 		rs145858198
- 0.0001 -
77_CYS TRP 8.3kJPN
chr1:110200268 		rs1314408786
- 0.0001 -
77_ARG CYS 8.3kJPN
chr1:110256160 		rs147739570
- 0.0001 -
81_ARG CYS gnomAD
chr1:110231736 		rs781451004
- 0.000679769 -
81_ARG CYS 8.3kJPN
chr1:110200278 		rs201193976
- 0.0001 -
81_ARG HIS 8.3kJPN
chr1:110200279 		rs750577198
- 0.0014 -
81_ARG HIS 8.3kJPN
chr1:110211979 		rs769666982
- 0.0003 -
84_ASN SER gnomAD
chr1:110231746 		rs147668562
- 0.0381248 -
84_ASN LYS gnomAD
chr1:110231747 		rs146668816
- 0.000219242 -
95_ARG PRO gnomAD
chr1:110212120 		rs140675803
- 0.000174978 -
95_ARG CYS 8.3kJPN
chr1:110200420 		rs761147429
- 0.0001 -
95_ARG PRO 8.3kJPN
chr1:110212120 		rs140675803
- 0.0005 -
95_ARG LEU 8.3kJPN
chr1:110231874 		rs199816990
- 0.013 -
95_ARG LEU 8.3kJPN
chr1:110256310 		rs148956224
- 0.0071 -
96_VAL MET 8.3kJPN
chr1:110200423 		-
- 0.0001 -
103_VAL ILE 8.3kJPN
chr1:110256333 		rs756521706
- 0.0002 -
103_VAL ALA 8.3kJPN
chr1:110256334 		rs766842191
- 0.0002 -
104_MET THR 8.3kJPN
chr1:110231901 		rs202002774
- 0.0187 -
104_MET THR 8.3kJPN
chr1:110256337 		rs1326916949
- 0.0002 -
105_ASP GLU 8.3kJPN
chr1:110212151 		-
- 0.0001 -
106_ASN LYS gnomAD
chr1:110256344 		rs144915668
- 0.000107421 -
109_GLN TER 8.3kJPN
chr1:110200462 		rs1223667143
- 0.0001 -
110_LEU VAL 8.3kJPN
chr1:110256354 		-
- 0.0001 -
111_GLY VAL 8.3kJPN
chr1:110231922 		rs1179816349
- 0.0129 -
113_LEU GLN gnomAD
chr1:110256364 		rs144530836
- 0.00100068 -
114_CYS TYR gnomAD
chr1:110200478 		rs557974260
- 0.000111344 -
114_CYS TYR 8.3kJPN
chr1:110200478 		rs557974260
- 0.0007 -
115_TYR HIS gnomAD
chr1:110200480 		rs576929306
- 0.000170989 -
116_ASN HIS 8.3kJPN
chr1:110231936 		rs1363667431
- 0.0108 -
138_SER LEU 8.3kJPN
chr1:110257624 		-
- 0.0001 -
139_GLN TER 8.3kJPN
chr1:110201493 		-
- 0.0001 -
144_ARG TRP gnomAD
chr1:110232965 		rs142484086
- 0.0015642 -
144_ARG TRP gnomAD
chr1:110257641 		rs140499099
- 0.00949151 -
144_ARG TRP 8.3kJPN
chr1:110232965 		rs142484086
- 0.0003 -
144_ARG TRP 8.3kJPN
chr1:110257641 		rs140499099
- 0.0075 -
146_TRP ARG gnomAD
chr1:110257647 		rs150881777
- 0.00026244 -
146_TRP TER 8.3kJPN
chr1:110213989 		-
- 0.0001 -
148_LEU ILE 8.3kJPN
chr1:110213993 		-
- 0.0014 -
149_GLY GLU gnomAD
chr1:110201524 		rs760050912
- 0.000111335 -
149_GLY ARG 8.3kJPN
chr1:110201523 		rs776935872
- 0.0001 -
149_GLY GLU 8.3kJPN
chr1:110201524 		rs760050912
- 0.0001 -
150_ASN ASP gnomAD
chr1:110232983 		rs140584594
- 0.00174608 -
151_LYS GLU 8.3kJPN
chr1:110257662 		rs778331898
- 0.0011 -
158_LEU VAL gnomAD
chr1:110233094 		rs138440339
- 0.00031646 -
159_ALA THR gnomAD
chr1:110201643 		rs147618175
- 0.000218691 -
161_ASP VAL gnomAD
chr1:110233104 		rs544766466
- 0.000483405 -
163_LEU ARG 8.3kJPN
chr1:110257786 		-
- 0.0001 -
165_LEU ILE gnomAD
chr1:110233115 		rs149344762
- 0.0143247 -
166_HIS ASN gnomAD
chr1:110233118 		rs146001438
- 0.0154707 -
166_HIS GLN gnomAD
chr1:110233120 		rs143315534
- 0.0188043 -
167_ARG CYS gnomAD
chr1:110201667 		rs114328674
- 0.00109346 -
167_ARG CYS gnomAD
chr1:110233121 		rs375154572
- 0.000186931 -
167_ARG CYS 8.3kJPN
chr1:110257797 		rs761981861
- 0.0017 -
172_LYS ASN VAR_003617 rs1065411
LB/B - -
172_ASN LYS gnomAD
chr1:110201684 		rs147265487
- 0.000238572 -
172_LYS ASN gnomAD
chr1:110233138 		rs1065411
- 0.361675 -
172_LYS ASN gnomAD
chr1:110257814 		rs78955679
- 0.00598021 -
172_SER ASN 8.3kJPN
chr1:110214156 		rs2229050
- 0.0001 -
172_LYS ARG 8.3kJPN
chr1:110233137 		rs769295127
- 0.0005 -
172_LYS ASN 8.3kJPN
chr1:110233138 		rs1065411
- 0.7472 -
172_LYS ASN 8.3kJPN
chr1:110257814 		rs78955679
- 0.0743 -
176_ALA VAL gnomAD
chr1:110257825 		rs376313197
- 0.000119296 -
178_LEU PRO gnomAD
chr1:110257831 		rs2227963
- 0.0873792 -
180_LEU VAL 8.3kJPN
chr1:110214179 		-
- 0.0001 -
183_PHE LEU 8.3kJPN
chr1:110214190 		rs1557958959
- 0.0001 -
185_SER PHE 8.3kJPN
chr1:110214195 		-
- 0.0001 -
186_ARG HIS gnomAD
chr1:110233179 		rs753904217
- 0.000192694 -
186_ARG CYS gnomAD
chr1:110257854 		rs150417585
- 0.00560247 -
186_ARG HIS gnomAD
chr1:110257855 		rs137869431
- 0.000159048 -
201_ARG CYS gnomAD
chr1:110203823 		rs150650325
- 0.00043381 -
201_ARG HIS 8.3kJPN
chr1:110235865 		rs371247780
- 0.0001 -
204_ARG TER 8.3kJPN
chr1:110260004 		rs181150599
- 0.0012 -
205_ARG LYS 8.3kJPN
chr1:110217418 		rs527715023
- 0.0005 -
209_SER THR VAR_014497 rs449856
LB/B - -
209_SER THR 8.3kJPN
chr1:110235888 		rs449856
- 0.0029 -
210_LYS ARG 8.3kJPN
chr1:110260023 		-
- 0.0001 -
211_VAL MET gnomAD
chr1:110203853 		rs149370166
- 0.0011034 -
212_ALA VAL gnomAD
chr1:110217439 		rs201667505
- 0.000139172 -
216_SER GLY gnomAD
chr1:110260040 		rs113130058
- 0.00813648 -
(Powered by wupsivus)

Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.