PDB ID 2F7S     CHAIN A
Protein name Ras-related protein Rab-27B
Uniprot Accession O00194
The number of similar proteins 6
The number of binding states 3
The number of binding partners 2

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2F7S (CHAIN: A)
1 O00194  
2 Monomeric state
3 Q91V27  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   MGSSHHHHHH   SSGLVPRGSG   DYDYLIKLLA   LGDSGVGKTT   FLYRYTDNKF   50
51   NPKFITTVGI   DFREKRVVYN   AQGPNGSSGK   AFKVHLQLWD   TAGQERFRSL   100
101   TTAFFRDAMG   FLLMFDLTSQ   QSFLNVRNWM   SQLQANAYCE   NPDIVLIGNK   150
151   ADLPDQREVN   ERQARELADK   YGIPYFETSA   ATGQNVEKAV   ETLLDLIMKR   200
201   MEQCVEKTQI   PDTVNGG         250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
28_ARG LYS 8.3kJPN
chr18:52544899 		rs764729616
- 0.0001 -
66_PHE LEU gnomAD
chr18:52546642 		rs200080884
- 0.000163143 -
92_ALA THR VAR_051714 rs9966265
LB/B - -
92_ALA THR gnomAD
chr18:52551598 		rs9966265
- 0.000398527 -
128_ILE MET 8.3kJPN
chr18:52555266 		rs1457602591
- 0.0005 -
129_VAL ILE 8.3kJPN
chr18:52555267 		rs372053847
- 0.0001 -
138_PRO LEU gnomAD
chr18:52555295 		rs77350395
- 0.000362998 -
146_ARG GLN 8.3kJPN
chr18:52555319 		rs184898936
- 0.0005 -
161_GLU LYS 8.3kJPN
chr18:52556468 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.