PDB ID 2FY5 CHAINA
Protein nameCHOLINE O-ACETYLTRANSFERASE
Uniprot Accession P28329
The number of similar proteins 4
The number of binding states 1
The number of binding partners 0
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
2FY5 (CHAIN: A)
1 Monomeric state
Downdload
Format:
Molecule viewer
#binding
partners
  0
Sequence information
1  AAAKTPSSEE   SGLPKLPVPP   LQQTLATYLQ   CMRHLVSEEQ   FRKSQAIVQQ   50
51  FGAPGGLGET   LQQKLLERQE   KTANWVSEYW   LNDMYLNNRL   ALPVNSSPAV   100
101  IFARQHFPGT   DDQLRFAASL   ISGVLSYKAL   LDSHSIPTDC   AKGQLSGQPL   150
151  CMKQYYGLFS   SYRLPGHTQD   TLVAQNSSIM   PEPEHVIVAC   CNQFFVLDVV   200
201  INFRRLSEGD   LFTQLRKIVK   MASNAAARLP   PIGLLTSDGR   SEWAEARTVL   250
251  VKDSTNRDSL   DMIERCICLV   CLDAPGGVEL   SDTHRALQLL   HGGGYSKNGA   300
301  NRWYDKSLQF   VVGRDGTCGV   VCEHSPFDGI   VLVQCTEHLL   KHMTQPELVR   350
351  SPMVPLPAPR   RLRWKCSPEI   QGHLASSAEK   LQRIVKNLDF   IVYKFDNYGK   400
401  TFIKKQKCSP   DAFIQVALQL   AFYRLHRRLV   PTYESASIRR   FQEGRVDNIR   450
451  SATPEALAFV   RAVTDHKAAV   PASEKLLLLK   DAIRAQTAYT   VMAITGMAID   500
501  NHLLALRELA   RAMCAALPEM   FMDETYLMSN   RFVLSTSQVP   TTTEMFCCYG   550
551  PVVPNGYGAC   YNPQPETILF   CISSFHSCAA   TSSSKFAKAV   EESLIDMRDL   600
601  CSLLPPTESK   PL                                             650
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
92_LEU PRO VAR_011666 rs121912820 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
93_PRO ALA VAR_011667 rs121912815 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
104_ARG PRO VAR_046684 rs8178989 Polymorphism -
125_LEU PHE VAR_046685 rs8178990 Polymorphism -
181_PRO LEU VAR_046686 rs868749 Polymorphism -
187_ILE THR VAR_011668 rs75466054 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
218_ILE THR VAR_038605 rs121912823 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
274_ALA GLY VAR_011676 - Polymorphism -
282_ASP ASN VAR_046687 rs8178991 Polymorphism -
302_ARG CYS VAR_011669 rs121912822 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
323_GLU LYS VAR_011670 rs121912816 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
364_ARG GLY VAR_011671 rs121912818 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
380_SER LEU VAR_011672 rs121912821 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
388_VAL LEU VAR_011673 rs121912817 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]
442_ARG HIS VAR_011674 rs121912819 Disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6) [MIM:254210]