PDB ID 2GAJ     CHAIN A
Protein name DNA topoisomerase I
Uniprot Accession P46799
The number of similar proteins 2
The number of binding states 1
The number of binding partners 0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2GAJ (CHAIN: A)
1 Monomeric state

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  0

Sequence information

1   MAKKVKKYIV   VESPAKAKTI   KSILGNEYEV   FASMGHIIDL   PKSKFGVDLE   50
51   KDFEPEFAVI   KGKEKVVEKL   KDLAKKGELL   IASDMDREGE   AIAWHIARVT   100
101   NTLGRKNRIV   FSEITPRVIR   EAVKNPREID   MKKVRAQLAR   RILDRIVGYS   150
151   LSPVLWRNFK   SNLSAGRVQS   ATLKLVCDRE   REILRFVPKK   YHRITVNFDG   200
201   LTAEIDVKEK   KFFDAETLKE   IQSIDELVVE   EKKVSVKKFA   PPEPFKTSTL   250
251   QQEAYSKLGF   SVSKTMMIAQ   QLYEGVETKD   GHIAFITYMR   TDSTRVSDYA   300
301   KEEARNLITE   VFGEEYVGSK   RERRKSNAKI   QDAHEAIRPT   NVFMTPEEAG   350
351   KYLNSDQKKL   YELIWKRFLA   SQMKPSQYEE   TRFVLRTKDG   KYRFKGTVLK   400
401   KIFDGYEKVW   KTERNTGEFP   FEEGESVKPV   VVKIEEQETK   PKPRYTEGSL   450
451   VKEMERLGIG   RPSTYASTIK   LLLNRGYIKK   IRGYLYPTIV   GSVVMDYLEK   500
501   KYSDVVSVSF   TAEMEKDLDE   VEQGKKTDKI   VLREFYESFS   SVFDRNDRIV   550
551   VDFPTNQKCS   CGKEMRLSFG   KYGFYLKCEC   GKTRSVKNDE   IAVIDDGKIF   600
601   LGRKDSESGS   PDGRSVEGKG   NLSEKRRKGK   KGS     650

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.