PDB ID 2GQI     CHAIN A
Protein name Ras GTPase-activating protein 1
Uniprot Accession P20936
The number of similar proteins 8
The number of binding states 3
The number of binding partners 2

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2GQI (CHAIN: A)
1 Monomeric state
2 Q96QB1-6  
3 2J05  

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Format:

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Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   GSSGSSGRRV   RAILPYTKVP   DTDEISFLKG   DMFIVHNELE   DGWMWVTNLR   50
51   TDEQGLIVED   LVEEVSGPSS   G       100

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
11_ARG TER ClinVar
chr5:86629108 		rs137853218
Pathogenic - Capillary malformation-arteriovenous malformation 1|Capillary malformation-arteriovenous malformation syndrome|Vascular malformation [MONDO:MONDO:0020783,MedGen:C4747394,OMIM:608354,Orphanet:137667,Orphanet:90307|MONDO:MONDO:0012016,MedGen:C1842180,OMIM:PS608354,Orphanet:137667|MONDO:MONDO:0024291,MedGen:C0158570]
45_TRP TER ClinVar
chr5:86633848 		-
Pathogenic - Capillary malformation-arteriovenous malformation syndrome [MONDO:MONDO:0012016,MedGen:C1842180,OMIM:PS608354,Orphanet:137667]
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.