PDB ID 2ILK     CHAIN A
Protein name INTERLEUKIN-10
Uniprot Accession P22301
The number of similar proteins 9
The number of binding states 3
The number of binding partners 3

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2ILK (CHAIN: A)
1 Monomeric state
2 Q13651  
3 1LK3   1LK3  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   SPGQGTQSEN   SCTHFPGNLP   NMLRDLRDAF   SRVKTFFQMK   DQLDNLLLKE   50
51   SLLEDFKGYL   GCQALSEMIQ   FYLEEVMPQA   ENQDPDIKAH   VNSLGENLKT   100
101   LRLRLRRCHR   FLPCENKSKA   VEQVKNAFNK   LQEKGIYKAM   SEFDIFINYI   150
151   EAYMTMKIRN           200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
22_MET VAL 8.3kJPN
chr1:206945663 		rs755837237
- 0.001 -
84_ASP ALA 8.3kJPN
chr1:206944325 		-
- 0.0011 -
95_GLY ALA 8.3kJPN
chr1:206944292 		-
- 0.0001 -
106_ARG GLN gnomAD
chr1:206944259 		rs201365412
- 0.000119331 -
106_ARG GLN 8.3kJPN
chr1:206944259 		rs201365412
- 0.0058 -
107_ARG SER 8.3kJPN
chr1:206944257 		rs771912629
- 0.0001 -
117_LYS GLU 8.3kJPN
chr1:206943215 		-
- 0.0004 -
127_ALA VAL 8.3kJPN
chr1:206943184 		rs774072665
- 0.0001 -
149_TYR CYS 8.3kJPN
chr1:206942018 		-
- 0.0001 -
159_ARG TER 8.3kJPN
chr1:206941989 		rs142726516
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.