PDB ID 2J05     CHAIN A
Protein name RAS GTPASE-ACTIVATING PROTEIN 1
PDB 2J05
The number of similar proteins 8
The number of binding states 3
The number of binding partners 2

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
2J05 (CHAIN: A)
1 2J05  
2 Monomeric state
3 Q96QB1-6  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   GSHXRRRVRA   ILPYTKVPDT   DEISFLKGDX   FIVHNELEDG   WXWVTNLRTD   50
51   EQGLIVEDLV   EEVGR         100

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
281_ARG TER ClinVar
chr5:86629096
-
Pathogenic - Capillary malformation-arteriovenous malformation syndrome [MONDO:MONDO:0012016,MedGen:C1842180,OMIM:PS608354,Orphanet:137667]
285_ARG TER ClinVar
chr5:86629108
rs137853218
Pathogenic - Capillary malformation-arteriovenous malformation 1|Capillary malformation-arteriovenous malformation syndrome|Vascular malformation [MONDO:MONDO:0020783,MedGen:C4747394,OMIM:608354,Orphanet:137667,Orphanet:90307|MONDO:MONDO:0012016,MedGen:C1842180,OMIM:PS608354,Orphanet:137667|MONDO:MONDO:0024291,MedGen:C0158570]
319_TRP TER ClinVar
chr5:86633848
-
Pathogenic - Capillary malformation-arteriovenous malformation syndrome [MONDO:MONDO:0012016,MedGen:C1842180,OMIM:PS608354,Orphanet:137667]
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.