PiSITE

PDB ID	2JU4	CHAIN	A
Protein name	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Uniprot Accession	P04972
The number of similar proteins	1
The number of binding states	1
The number of binding partners	0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding state	Binding partners
	2JU4 (CHAIN: A)
1	Monomeric state

Downdload

Molecule viewer

Only interaction residues

#binding
partners

Sequence information

MNLEPPKAEC

RSATRVMGGP

CTPRKGPPKC

KQRQTRQCKS

KPPKKGVQGC

GDDIPGMEGC

GTDITVICPW

EACNHCELHE

LAQYGIC

100

Variants

Residue	AA	Source	dbSNP	Clinical Significance	Allele Frequency (> 0.0001)	Disease name
2_ASN	LYS	8.3kJPN chr17:79620330	rs766951952	-	0.0002	-
18_GLY	ARG	8.3kJPN chr17:79620284	rs769825057	-	0.0001	-
25_LYS	ARG	gnomAD chr17:79620262	rs113370432	-	0.000196893	-
27_PRO	ALA	8.3kJPN chr12:15131013	-	-	0.0001	-
32_GLN	GLU	8.3kJPN chr12:15131028	-	-	0.0001	-
33_ARG	TER	ClinVar chr17:79620239	-	Pathogenic	-	not provided [MedGen:C3661900]
39_LYS	ASN	gnomAD chr17:79620219	rs181137206	-	0.000124476	-
39_LYS	ASN	8.3kJPN chr17:79620219	-	-	0.0001	-
44_LYS	GLN	8.3kJPN chr17:79620206	-	-	0.0001	-
47_VAL	GLY	gnomAD chr17:79620196	rs535048114	-	0.000397533	-
49_GLY	ARG	8.3kJPN chr12:15131079	-	-	0.0001	-
53_ASP	ASN	8.3kJPN chr17:79618705	rs144191975	-	0.0001	-
59_GLY	SER	8.3kJPN chr17:79618687	rs372592115	-	0.0001	-
76_LEU	MET	gnomAD chr12:15134372	rs200270994	-	0.0001392	-
76_LEU	MET	8.3kJPN chr12:15134372	rs200270994	-	0.0004	-
80_GLU	LYS	8.3kJPN chr17:79618130	rs1327309562	-	0.0001	-
82_ALA	SER	gnomAD chr12:15134390	rs199740819	-	0.001245	-
82_ALA	THR	8.3kJPN chr17:79618124	-	-	0.0002	-
83_GLN	HIS	gnomAD chr12:15134395	rs564659543	-	0.00015909	-

(Powered by wupsivus)

Reference