PDB ID 2K31     CHAIN A
Protein name Phosphodiesterase 5A, cGMP-specific
Uniprot Accession Q0VBW0
The number of similar proteins 1
The number of binding states 1
The number of binding partners 0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
2K31 (CHAIN: A)
1 Monomeric state

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  0

Sequence information

1   MDVTALCHKI   FLHIHGLISA   DRYSLFLVCE   DSSKDKFLIS   RLFDVAEGST   50
51   LEEASNNCIR   LEWNKGIVGH   VAAFGEPLNI   KDAYEDPRFN   AEVDQITGYK   100
101   TQSILCMPIK   NHREEVVGVA   QAINKKSGNG   GTFTEKDEKD   FAEYLAFCGE   150
151   VLHNAQLYET   SLLENKRNLE   HHHHHH       200

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
171_SER ALA gnomAD
chr4:120528064
rs17051276
- 0.0412128 -
171_SER ALA 8.3kJPN
chr4:120528064
rs17051276
- 0.0253 -
179_LEU PHE gnomAD
chr4:120528040
rs201501062
- 0.000310272 -
186_ASN SER 8.3kJPN
chr4:120528018
rs370533932
- 0.0001 -
193_ARG HIS 8.3kJPN
chr4:120527997
rs964954525
- 0.0001 -
212_ARG HIS 8.3kJPN
chr4:120527940
rs200971951
- 0.0001 -
229_PRO THR 8.3kJPN
chr4:120527890
-
- 0.0001 -
265_ARG THR gnomAD
chr4:120517685
rs200880547
- 0.000135192 -
267_GLU LYS 8.3kJPN
chr4:120517680
-
- 0.0001 -
(Powered by wupsivus)

Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.