PDB ID 2PWN     CHAIN A
Protein name Trafficking protein particle complex subunit 3
Uniprot Accession O55013
The number of similar proteins 10
The number of binding states 5
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
2PWN (CHAIN: A)
1 Monomeric state
2 Q6DGL5  
3 Q86SZ2  
4 Q6DGL5   2J3W  
5 O75865   Q9Y296   Q5NCF2  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   GSDKIHHHHH   HXSRQANRGT   ESKKXSSELF   TLTYGALVTQ   LCKDYENDED   50
51   VNKQLDRXGY   NIGVRLIEDF   LARSNVGRCH   DFRETADVIA   KVAFKXYLGI   100
101   TPSITNWSPA   GDEFSLILEN   NPLVDFVELP   DNHSALIYSN   LLCGVLRGAL   150
151   EXVQXAVEAK   FVQDTLKGDG   VTEIRXRFIR   RIEDNLPAGE   E   200

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
62_ARG TRP ClinVar
chr1:36605377
rs751375244
Likely pathogenic - Bardet-Biedl syndrome [MONDO:MONDO:0015229,MedGen:C0752166,OMIM:PS209900,Orphanet:110]
62_ARG PRO 8.3kJPN
chr1:36605376
-
- 0.0001 -
76_ASP GLY 8.3kJPN
chr1:36605334
-
- 0.0001 -
92_SER GLY gnomAD
chr1:36603546
rs138894050
- 0.0002387 -
129_ASN SER 8.3kJPN
chr1:36603434
rs758862062
- 0.0001 -
131_LEU PHE gnomAD
chr1:36603427
rs141225393
- 0.000175 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.