PDB ID 2QL5     CHAIN A
Protein name Caspase-7
Uniprot Accession P55210
The number of similar proteins 48
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2QL5 (CHAIN: A)
1 P55210   P55210   P55210  
2 P55210  
3 P55210   4JB8  
4 P55210   P55210   P55210   4LSZ  
5 P55210   P55210   P55210   P98170  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   AKPDRSSFVP   SLFSKKKKNV   TMRSIKTTRD   RVPTYQYNMN   FEKLGKCIII   50
51   NNKNFDKVTG   MGVRNGTDKD   AEALFKCFRS   LGFDVIVYND   CSCAKMQDLL   100
101   KKASEEDHTN   AACFACILLS   HGEENVIYGK   DGVTPIKDLT   AHFRGDRCKT   150
151   LLEKPKLFFI   QACRGTELDD   GIQ       200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
62_MET LEU 8.3kJPN
chr10:115480864 		-
- 0.0001 -
75_ASN LYS 8.3kJPN
chr10:115480905 		-
- 0.0001 -
86_VAL ILE gnomAD
chr10:115481418 		rs115183028
- 0.000111349 -
89_GLY ARG 8.3kJPN
chr10:115481427 		rs757905204
- 0.0001 -
96_ALA VAL 8.3kJPN
chr10:115481449 		rs1482095638
- 0.0001 -
98_PHE LEU 8.3kJPN
chr10:115481454 		rs1383138083
- 0.0001 -
102_ARG GLN gnomAD
chr10:115481467 		rs146796754
- 0.000198826 -
121_ASP GLU 8.3kJPN
chr10:115481525 		rs368309877
- 0.0001 -
136_CYS PHE 8.3kJPN
chr10:115485151 		rs1018566256
- 0.0001 -
169_ASP TYR 8.3kJPN
chr10:115485249 		-
- 0.0001 -
171_CYS SER gnomAD
chr10:115485256 		rs201040237
- 0.000179947 -
181_PHE LEU gnomAD
chr10:115485285 		rs141266925
- 0.00426735 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.