PDB ID 2VXT     CHAIN I
Protein name INTERLEUKIN-18
Uniprot Accession Q14116
The number of similar proteins 16
The number of binding states 7
The number of binding partners 8

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2VXT (CHAIN: I)
1 2VXT   2VXT  
2 Monomeric state
3 Q13478  
4 Q9IW12  
5 Q9DHU8  
6 Q13478   O95256  
7 P49662   P49662  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   YFGKLESKLS   VIRNLNDQVL   FIDQGNRPLF   EDMTDSDARD   NAPRTIFIIS   50
51   MYKDSQPRGM   AVTISVKAEK   ISTLSAENKI   ISFKEMNPPD   NIKDTKSDII   100
101   FFQRSVPGHD   NKMQFESSSY   EGYFLAAEKE   RDLFKLILKK   EDELGDRSIM   150
151   FTVQNED           200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
47_VAL ILE gnomAD
chr11:112020882 		rs567330603
- 0.000153539 -
71_ASP GLY 8.3kJPN
chr11:112020809 		-
- 0.0001 -
76_ASP GLY 8.3kJPN
chr11:112019459 		-
- 0.0001 -
80_ARG GLN 8.3kJPN
chr11:112019447 		rs768843343
- 0.0001 -
129_LYS ASN 8.3kJPN
chr11:112014514 		-
- 0.0001 -
167_ARG LYS 8.3kJPN
chr11:112014401 		rs199644300
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.