PDB ID 2ZVO CHAIN B
Protein name NF-kappa-B essential modulator
Uniprot Accession O88522
The number of similar proteins 12
The number of binding states 6
The number of binding partners 5
Coloring
Unicolor (beige)
The number of binding partners
Group

Downdload
 Format:  
Molecule viewer
#binding
partners
  5
  4
  3
  2
  1
  0
Sequence information
1   GSGMQLEDLR   QQLQQAEEAL   VAKQELIDKL   KEEAAQHAIV   METVPVLKAQ   50
51   ADIYKADFQA   ERHAREKLVE   KKEYLQEQLE   QLQREFNKLK   VG   100
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
281_ALA GLY ClinVar
chrX:153791119
rs137853330 Pathogenic Hypohidrotic ectodermal dysplasia with immune deficiency [MedGen:C1846006,OMIM:300291,Orphanet:ORPHA98813]
283_GLN TER ClinVar
chrX:153791124
rs1156900338 Pathogenic not provided [MedGen:CN517202]
304_ASP ASN ClinVar
chrX:153791792
rs179363867 Likely pathogenic Hypohidrotic ectodermal dysplasia with immune deficiency [MedGen:C1846006,OMIM:300291,Orphanet:ORPHA98813]; not provided [MedGen:CN517202]
308_GLU ALA ClinVar
chrX:153791805
rs137853331 Pathogenic Familial atypical mycobacteriosis, type 1, X-linked [MedGen:C1970879,OMIM:300636,Orphanet:ORPHA319612]
312_ARG GLN ClinVar
chrX:153791817
rs137853332 Pathogenic Familial atypical mycobacteriosis, type 1, X-linked [MedGen:C1970879,OMIM:300636,Orphanet:ORPHA319612]