PDB ID 3BGV     CHAIN A
Protein name mRNA cap guanine-N7 methyltransferase
Uniprot Accession O43148
The number of similar proteins 4
The number of binding states 2
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3BGV (CHAIN: A)
1 Monomeric state
2 Q9BTL3  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   GSQSRIFYLR   NFNNWMKSVL   IGEFLEKVRQ   KKKRDITVLD   LGCGKGGDLL   50
51   KWKKGRINKL   VCTDIADVSV   KQCQQRYEDM   KNRRDSEYIF   SAEFITADSS   100
101   KELLIDKFRD   PQMCFDICSC   QFVCHYSFES   YEQADMMLRN   ACERLSPGGY   150
151   FIGTTPNSFE   LIRRLEASET   ESFGNEIYTV   KFQKKGDYPL   FGCKYDFNLE   200
201   GVVDVPEFLV   YFPLLNEMAK   KYNMKLVYKK   TFLEFYEEKI   KNNENKMLLK   250
251   RMQALEPYPA   NESSKLVSEK   VDDYEHAAKY   MKNSQVRLPL   GTLSKSEWEA   300
301   TSIYLVFAFE   KQQ         350

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
31_LYS ARG 8.3kJPN
chr18:13737039 		-
- 0.0001 -
57_ASN THR 8.3kJPN
chr18:13737117 		rs1229079417
- 0.0002 -
75_ARG GLN 8.3kJPN
chr18:13740202 		rs1438601973
- 0.0001 -
83_ARG CYS 8.3kJPN
chr18:13740225 		rs116111155
- 0.01 -
83_ARG HIS 8.3kJPN
chr18:13740226 		rs752711714
- 0.0001 -
85_SER GLY gnomAD
chr18:13740231 		rs202093575
- 0.000139728 -
104_ILE THR gnomAD
chr18:13741519 		rs116831898
- 0.000181088 -
124_HIS ARG 8.3kJPN
chr18:13741579 		-
- 0.0001 -
153_THR ILE 8.3kJPN
chr18:13741666 		-
- 0.0001 -
163_ARG CYS 8.3kJPN
chr18:13742491 		rs780942591
- 0.0001 -
191_GLY SER 8.3kJPN
chr18:13742575 		-
- 0.0001 -
221_TYR CYS 8.3kJPN
chr18:13746233 		-
- 0.0001 -
225_LEU VAL 8.3kJPN
chr18:13746244 		-
- 0.0001 -
239_ILE SER 8.3kJPN
chr18:13746287 		-
- 0.0003 -
246_MET ILE gnomAD
chr18:13746309 		rs376815436
- 0.000104181 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.