PDB ID 3BO5     CHAIN A
Protein name Histone-lysine N-methyltransferase SETMAR
Uniprot Accession Q53H47
The number of similar proteins 1
The number of binding states 1
The number of binding partners 0

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3BO5 (CHAIN: A)
1 Monomeric state

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  0

Sequence information

1   GAEFKEKPEA   PTEQLDVACG   QENLPVGAWP   PGAAPAPFQY   TPDHVVGPGA   50
51   DIDPTQITFP   GCICVKTPCL   PGTCSCLRHG   ENYDDNSCLR   DIGSGGKYAE   100
101   PVFECNVLCR   CSDHCRNRVV   QKGLQFHFQV   FKTHKKGWGL   RTLEFIPKGR   150
151   FVCEYAGEVL   GFSEVQRRIH   LQTKSDSNYI   IAIREHVYNG   QVMETFVDPT   200
201   YIGNIGRFLN   HSCEPNLLMI   PVRIDSMVPK   LALFAAKDIV   PEEELSYDYS   250
251   GRYLNLTVSA   SKERLDHGKL   RKPCYCGAKS   CTAFLPFDSS     300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
29_PRO LEU 8.3kJPN
chr3:4345182 		-
- 0.0001 -
30_PRO SER gnomAD
chr3:4345184 		rs60314351
- 0.00560597 -
30_PRO LEU 8.3kJPN
chr3:4345185 		rs1236145530
- 0.0003 -
49_ALA THR 8.3kJPN
chr3:4354612 		-
- 0.0001 -
53_PRO ALA 8.3kJPN
chr3:4354624 		-
- 0.0001 -
75_CYS TYR 8.3kJPN
chr3:4354691 		-
- 0.0001 -
77_ARG HIS gnomAD
chr3:4354697 		rs6801634
- 0.129467 -
77_ARG HIS 8.3kJPN
chr3:4354697 		rs6801634
- 0.103 -
90_ASP ASN 8.3kJPN
chr3:4354735 		-
- 0.0001 -
99_GLU ASP 8.3kJPN
chr3:4354764 		-
- 0.0001 -
109_ARG TER 8.3kJPN
chr3:4354792 		rs746229986
- 0.0001 -
112_ASP GLY gnomAD
chr3:4354802 		rs150691823
- 0.00687861 -
120_GLN LEU gnomAD
chr3:4354826 		rs138879830
- 0.00017911 -
124_GLN TER 8.3kJPN
chr3:4354837 		-
- 0.0001 -
132_THR MET gnomAD
chr3:4354862 		rs746079872
- 0.000103491 -
146_PRO LEU 8.3kJPN
chr3:4354904 		rs759135878
- 0.0001 -
156_GLY SER gnomAD
chr3:4354933 		rs764005838
- 0.000107637 -
171_GLN HIS 8.3kJPN
chr3:4354980 		rs1222497598
- 0.0001 -
202_GLY TER 8.3kJPN
chr3:4355071 		rs756547868
- 0.0013 -
222_ARG TER 8.3kJPN
chr3:4355131 		rs568818086
- 0.0001 -
224_ASP ALA gnomAD
chr3:4355138 		rs61731496
- 0.00328175 -
227_VAL ALA 8.3kJPN
chr3:4355147 		-
- 0.0001 -
228_PRO ARG 8.3kJPN
chr3:4355150 		-
- 0.0004 -
245_SER CYS gnomAD
chr3:4355201 		rs200823423
- 0.000366826 -
245_SER CYS 8.3kJPN
chr3:4355201 		rs200823423
- 0.0001 -
250_GLY ARG 8.3kJPN
chr3:4355215 		rs767620834
- 0.0002 -
259_GLU LYS 8.3kJPN
chr3:4355242 		rs1191184107
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.