PDB ID 3BT2     CHAIN U
Protein name Urokinase plasminogen activator surface receptor
Uniprot Accession Q03405
The number of similar proteins 20
The number of binding states 8
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3BT2 (CHAIN: U)
1 3BT2   3BT2   P04004   P00749  
2 Monomeric state
3 Q03405  
4 P00749  
5 P04004   P00749  
6 4QTI   4QTI  
7 Q9UMV0   Q9UMV0   Q9UMV0  
8 Q52L64   Q4V9V8   P00749  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   RSLRCMQCKT   NGDCRVEECA   LGQDLCRTTI   VRLWEEGEEL   ELVEKSCTHS   50
51   EKTNRTLSYR   TGLKITSLTE   VVCGLDLCNQ   GNSGRAVTYS   RSRYLECISC   100
101   GSSDMSCERG   RHQSLQCRSP   EEQCLDVVTH   WIQEGEEGRP   KDDRHLRGCG   150
151   YLPGCPGSNG   FHNNDTFHFL   KCCNTTKCNE   GPILELENLP   QNGRQCYSCK   200
201   GNSTHGCSSE   ETFLIDCRGP   MNQCLVATGT   HEPKNQSYMV   RGCATASMCQ   250
251   HAHLGDAFSM   NHIDVSCCTK   SGCNHPDLDV   QYR     300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
4_MET ILE 8.3kJPN
chr19:44171821 		-
- 0.0001 -
16_GLU LYS 8.3kJPN
chr19:44171787 		-
- 0.0001 -
20_GLY VAL 8.3kJPN
chr19:44171774 		rs1201479506
- 0.0001 -
22_ASP HIS 8.3kJPN
chr19:44171769 		rs778790349
- 0.0001 -
23_LEU PHE 8.3kJPN
chr19:44171766 		-
- 0.0001 -
33_GLU GLY VAR_016322 rs4251813
LB/B - -
58_ARG TRP 8.3kJPN
chr19:44169540 		rs752525518
- 0.0001 -
64_THR ALA VAR_016323 rs399145
LB/B - -
64_THR ALA gnomAD
chr19:44169522 		rs399145
- 0.00823492 -
72_GLY GLU gnomAD
chr19:44169497 		rs150986089
- 0.00100602 -
74_ASP ASN 8.3kJPN
chr19:44169492 		-
- 0.0001 -
89_ARG GLN 8.3kJPN
chr19:44160771 		rs753893509
- 0.0001 -
91_ARG CYS 8.3kJPN
chr19:44160766 		rs531645411
- 0.0001 -
95_CYS ARG 8.3kJPN
chr19:44160754 		-
- 0.0002 -
109_ARG TRP 8.3kJPN
chr19:44160712 		rs772718099
- 0.0001 -
140_ASP GLY 8.3kJPN
chr19:44159713 		-
- 0.0001 -
145_ARG HIS 8.3kJPN
chr19:44159698 		rs1157998153
- 0.0001 -
149_TYR CYS 8.3kJPN
chr19:44159686 		rs763744500
- 0.0005 -
157_ASN SER gnomAD
chr19:44159662 		rs138306315
- 0.000242579 -
188_PRO LEU gnomAD
chr19:44156502 		rs141507706
- 0.000811385 -
198_LYS ARG VAR_016325 rs2302524
LB/B - -
198_LYS ARG gnomAD
chr19:44156472 		rs2302524
- 0.163056 -
198_LYS ARG 8.3kJPN
chr19:44156472 		rs2302524
- 0.1112 -
199_GLY ARG gnomAD
chr19:44156470 		rs542078792
- 0.000922546 -
209_GLU VAL 8.3kJPN
chr19:44156439 		-
- 0.0001 -
213_ILE THR 8.3kJPN
chr19:44156427 		-
- 0.0008 -
230_GLU LYS 8.3kJPN
chr19:44156377 		rs757884538
- 0.0002 -
237_MET THR 8.3kJPN
chr19:44153274 		-
- 0.0001 -
239_ARG LYS 8.3kJPN
chr19:44153268 		-
- 0.0001 -
246_MET VAL gnomAD
chr19:44153248 		rs138492321
- 0.00361124 -
255_ALA THR 8.3kJPN
chr19:44153221 		rs750492027
- 0.0001 -
259_ASN LYS VAR_016326 rs4251921
LB/B - -
259_ASN LYS gnomAD
chr19:44153207 		rs4251921
- 0.000866992 -
275_ASP ALA VAR_052698 rs16976608
LB/B - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.