PDB ID 3CON CHAINA
Protein nameGTPASE NRAS
Uniprot Accession P01111
The number of similar proteins 85
The number of binding states 11
The number of binding partners 9
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
3CON (CHAIN: A)
1 Monomeric state
2 Q07889
3 Q07889 Q07889
4 P20936
5 Q03386
6 P28829
7 Q9HBX6
8 P48736
9 P01112
10 P01112 P01112
11 2UZI 2UZI
Downdload
Format:
Molecule viewer
#binding
partners
  8
  7
  6
  5
  4
  3
  2
  1
  0
Sequence information
1  MHHHHHHSSG   RENLYFQGMT   EYKLVVVGAG   GVGKSALTIQ   LIQNHFVDEY   50
51  DPTIEDSYRK   QVVIDGETCL   LDILDTAGQE   EYSAMRDQYM   RTGEGFLCVF   100
101  AINNSKSFAD   INLYREQIKR   VKDSDDVPMV   LVGNKCDLPT   RTVDTKQAHE   150
151  LAKSYGIPFI   ETSAKTRQGV   EDAFYTLVRE   IRQYRMKKLN              200
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
12_GLY ASP VAR_071129 rs121913237 Disease Keratinocytic non-epidermolytic nevus (KNEN) [MIM:162900]
13_GLY ASP VAR_063084 rs121434596 Disease Leukemia, juvenile myelomonocytic (JMML) [MIM:607785]
34_PRO LEU VAR_071130 rs397514553 Disease Keratinocytic non-epidermolytic nevus (KNEN) [MIM:162900]
50_THR ILE VAR_063085 rs267606921 Disease Noonan syndrome 6 (NS6) [MIM:613224]
60_GLY GLU VAR_063086 rs267606920 Disease Noonan syndrome 6 (NS6) [MIM:613224]