PDB ID 3E4Z CHAIN A
Protein name Insulin-degrading enzyme
Uniprot Accession Q5T5N2
The number of similar proteins 53
The number of binding states 14
The number of binding partners 11
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
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partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0
Sequence information
1   MHHHHHHAAG   IPMNNPAIKR   IGNHITKSPE   DKREYRGLEL   ANGIKVLLIS   50
51   DPTTDKSSAA   LDVHIGSLSD   PPNIAGLSHF   LQHMLFLGTK   KYPKENEYSQ   100
101   FLSEHAGSSN   AFTSGEHTNY   YFDVSHEHLE   GALDRFAQFF   LSPLFDESAK   150
151   DREVNAVDSE   HEKNVMNDAW   RLFQLEKATG   NPKHPFSKFG   TGNKYTLETR   200
201   PNQEGIDVRQ   ELLKFHSAYY   SSNLMAVVVL   GRESLDDLTN   LVVKLFSEVE   250
251   NKNVPLPEFP   EHPFQEEHLK   QLYKIVPIKD   IRNLYVTFPI   PDLQKYYKSN   300
301   PGHYLGHLIG   HEGPGSLLSE   LKSKGWVNTL   VGGQKEGARG   FMFFIINVDL   350
351   TEEGLLHVED   IILHMFQYIQ   KLRAEGPQEW   VFQELKDLNA   VAFRFKDKER   400
401   PRGYTSKIAG   ILHYYPLEEV   LTAEYLLEEF   RPDLIEMVLD   KLRPENVRVA   450
451   IVSKSFEGKT   DRTEEWYGTQ   YKQEAIPDEV   IKKWQNADLN   GKFKLPTKNE   500
501   FIPTNFEILP   LEKEATPYPA   LIKDTAMSKL   WFKQDDKFFL   PKANLNFEFF   550
551   SPFAYVDPLH   SNMAYLYLEL   LKDSLNEYAY   AAELAGLSYD   LQNTIYGMYL   600
601   SVKGYNDKQP   ILLKKIIEKM   ATFEIDEKRF   EIIKEAYMRS   LNNFRAEQPH   650
651   QHAMYYLRLL   MTEVAWTKDE   LKEALDDVTL   PRLKAFIPQL   LSRLHIEALL   700
701   HGNITKQAAL   GIMQMVEDTL   IEHAHTKPLL   PSQLVRYREV   QLPDRGWFVY   750
751   QQRNEVHNNS   GIEIYYQTDM   QSTSENMFLE   LFAQIISEPA   FNTLRTKEQL   800
801   GYIVFSGPRR   ANGIQGLRFI   IQSEKPPHYL   ESRVEAFLIT   MEKSIEDMTE   850
851   EAFQKHIQAL   AIRRLDKPKK   LSAESAKYYG   EIISQQYNFD   RDNTEVAYLK   900
901   TLTKEDIIKF   YKEMLAVDAP   RRHKVSVHVL   AREMDSCPVV   GEFPCQNDIN   950
951   LSQAPALPQP   EVIQNMTEFK   RGLPLFPLVK   PHINFMAAKL     1000
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name