PDB ID 3LJR     CHAIN A
Protein name GLUTATHIONE S-TRANSFERASE
Uniprot Accession P30712
The number of similar proteins 10
The number of binding states 1
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3LJR (CHAIN: A)
1 P30712  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   MGLELFLDLV   SQPSRAVYIF   AKKNGIPLEL   RTVDLVKGQH   KSKEFLQINS   50
51   LGKLPTLKDG   DFILTESSAI   LIYLSCKYQT   PDHWYPSDLQ   ARARVHEYLG   100
101   WHADCIRGTF   GIPLWVQVLG   PLIGVQVPEE   KVERNRTAMD   QALQWLEDKF   150
151   LGDRPFLAGQ   QVTLADLMAL   EELMQPVALG   YELFEGRPRL   AAWRGRVEAF   200
201   LGAELCQEAH   SIILSILEQA   AKKTLPTPSP   EAYQAMLLRI   ARIP   250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
36_VAL ILE gnomAD
chr22:24322494 		rs967822924
- 0.0132027 -
36_VAL ILE 8.3kJPN
chr22:24322494 		rs967822924
- 0.0333 -
43_LYS ARG 8.3kJPN
chr22:24302553 		-
- 0.0001 -
54_LEU MET gnomAD
chr22:24323186 		rs538967136
- 0.000155268 -
56_THR MET 8.3kJPN
chr22:24302514 		rs1412501773
- 0.0002 -
56_THR MET 8.3kJPN
chr22:24323193 		rs373232513
- 0.0001 -
66_GLU LYS gnomAD
chr22:24302485 		rs781652428
- 0.00195744 -
66_GLU LYS gnomAD
chr22:24323222 		rs138324852
- 0.00148553 -
80_THR MET gnomAD
chr22:24324857 		rs554852319
- 0.00043122 -
80_THR MET 8.3kJPN
chr22:24300850 		rs777871541
- 0.0055 -
80_THR MET 8.3kJPN
chr22:24324857 		rs554852319
- 0.0008 -
113_PRO LEU gnomAD
chr22:24300751 		rs751153388
- 0.000219208 -
113_PRO ALA gnomAD
chr22:24300752 		-
- 0.000150347 -
113_PRO LEU gnomAD
chr22:24324956 		rs775227515
- 0.000122697 -
113_PRO ALA 8.3kJPN
chr22:24300752 		rs1302144216
- 0.0071 -
113_PRO ALA 8.3kJPN
chr22:24324955 		rs764989870
- 0.0049 -
118_VAL MET 8.3kJPN
chr22:24300645 		rs138877875
- 0.0059 -
118_VAL MET 8.3kJPN
chr22:24325062 		rs2301423
- 0.3296 -
123_ILE THR gnomAD
chr22:24300629 		rs530553575
- 0.000105795 -
123_ILE THR 8.3kJPN
chr22:24300629 		rs530553575
- 0.0001 -
129_LYS GLU gnomAD
chr22:24325095 		rs140195
- 0.0387907 -
129_GLU LYS 8.3kJPN
chr22:24300612 		rs565068798
- 0.0005 -
134_ARG HIS gnomAD
chr22:24300596 		rs143373337
- 0.000138943 -
135_ASN LYS gnomAD
chr22:24325115 		rs548564711
- 0.000131438 -
139_MET ILE gnomAD
chr22:24300580 		rs1622002
- 0.0530278 -
139_MET ILE gnomAD
chr22:24325127 		rs60718122
- 0.00147414 -
139_MET ILE 8.3kJPN
chr22:24300580 		rs1622002
- 0.1566 -
139_MET ILE 8.3kJPN
chr22:24325127 		rs60718122
- 0.0084 -
147_GLU LYS gnomAD
chr22:24325149 		rs146675046
- 0.00463743 -
153_ASP ASN gnomAD
chr22:24300540 		rs144128236
- 0.0203753 -
153_ASP ASN gnomAD
chr22:24325167 		rs4987176
- 0.0011575 -
158_ALA THR gnomAD
chr22:24325182 		rs139143959
- 0.0203453 -
160_GLN ARG gnomAD
chr22:24300518 		rs767811348
- 0.000179789 -
179_LEU PHE 8.3kJPN
chr22:24300110 		-
- 0.0001 -
188_PRO LEU gnomAD
chr22:24325625 		rs1052550288
- 0.000211506 -
196_ARG TER 8.3kJPN
chr22:24300059 		rs200376763
- 0.1526 -
196_ARG TER 8.3kJPN
chr22:24325648 		rs201176441
- 0.1604 -
197_VAL MET 8.3kJPN
chr22:24325651 		-
- 0.0003 -
216_ILE THR gnomAD
chr22:24325709 		rs1295520477
- 0.000122609 -
241_ALA THR gnomAD
chr22:24299924 		rs201431473
- 0.0217178 -
241_ALA THR gnomAD
chr22:24325783 		rs200087397
- 0.000663423 -
241_ALA THR 8.3kJPN
chr22:24325783 		rs200087397
- 0.0006 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.