PDB ID 5CBY CHAIN A
Protein name AncGR2 DNA Binding Domain
PDB 5CBY
The number of similar proteins 28
The number of binding states 2
The number of binding partners 1
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
5CBY (CHAIN: A)
1 5CBY  
2 Monomeric state
Downdload
 Format:  
Molecule viewer
#binding
partners
  1
  0
Sequence information
1   MHHHHHHSSG   VDLGTENLYF   QSNAGPPPKI   CLVCSDEASG   CHYGVLTCGS   50
51   CKVFFKRAVE   GQHNYLCAGR   NDCIIDKIRR   KNCPACRFRK   CLQAGMNLEA   100
101   RKTKK           150
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
451_GLY ARG ClinVar
chr4:149181130
rs121912566 Pathogenic Pseudohypoaldosteronism type 1 autosomal dominant [MedGen:C1449842,OMIM:177735,Orphanet:ORPHA171871]
463_CYS TER ClinVar
chr4:149115976
rs121912564 Pathogenic Pseudohypoaldosteronism type 1 autosomal dominant [MedGen:C1449842,OMIM:177735,Orphanet:ORPHA171871]
469_ARG TER ClinVar
chr4:149115960
rs1131691921 Likely pathogenic not provided [MedGen:CN517202]
477_ARG HIS ClinVar
chr5:142689700
rs104893913 Pathogenic Glucocorticoid resistance, generalized [MedGen:C1841972,OMIM:615962,Orphanet:ORPHA786]
491_ARG TER ClinVar
chr4:149076050
rs121912571 Likely pathogenic Pseudohypoaldosteronism type 1 autosomal dominant [MedGen:C1449842,OMIM:177735,Orphanet:ORPHA171871]