PDB ID 5WSV CHAIN A
Protein name Calmodulin
Uniprot Accession P62158
The number of similar proteins 206
The number of binding states 37
The number of binding partners 27
Coloring
Unicolor (beige)
The number of binding partners
Group

Downdload
 Format:  
Molecule viewer
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0
Sequence information
1   GPGSMADQLT   EEQIAEFKEA   FSLFDKDGDG   TITTKELGTV   MRSLGQNPTE   50
51   AELQDMINEV   DADGNGTIDF   PEFLTMMARK   MKDTDSEEEI   REAFRVFDKD   100
101   GNGYISAAEL   RHVMTNLGEK   LTDEEVDEMI   READIDGDGQ   VNYEEFVQMM   150
151   T           200
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
29_THR PRO ClinVar
chr14:90867656
rs1057521851 Likely pathogenic not provided [MedGen:CN517202]
53_ASN ILE ClinVar
chr14:90867729
rs267607276 Pathogenic/Likely pathogenic Catecholaminergic polymorphic ventricular tachycardia type 1 [MedGen:C4053736,OMIM:604772]; Ventricular tachycardia, catecholaminergic polymorphic, 4 [MedGen:C3554047,OMIM:614916]
89_PHE LEU ClinVar
chr14:90870295
rs730882253 Pathogenic Long QT syndrome 14 [MedGen:C4015671,OMIM:616247]
93_ASP ALA ClinVar
chr19:47111841
rs1060502608 Pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]
95_ASP VAL ClinVar
chr2:47388996
rs730882254 Pathogenic Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
97_ASN SER ClinVar
chr14:90870730
rs267607277 Pathogenic/Likely pathogenic Catecholaminergic polymorphic ventricular tachycardia [MedGen:C1631597,Orphanet:ORPHA3286]; Catecholaminergic polymorphic ventricular tachycardia type 1 [MedGen:C4053736,OMIM:604772]; Long QT syndrome 14 [MedGen:C4015671,OMIM:616247]; Ventricular tachycardia, catecholaminergic polymorphic, 4 [MedGen:C3554047,OMIM:614916]; Ventricular tachycardia, catecholaminergic polymorphic, 4 [MedGen:C3554047,OMIM:614916]
97_ASN SER ClinVar
chr2:47388990
rs398124647 Pathogenic/Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]; Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
97_ASN ILE ClinVar
chr2:47388990
rs398124647 Pathogenic/Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]; Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
104_GLU LYS ClinVar
chr14:90870750
rs1057523130 Likely pathogenic not provided [MedGen:CN517202]
129_ASP GLY ClinVar
chr14:90870826
rs730882252 Pathogenic Long QT syndrome 14 [MedGen:C4015671,OMIM:616247]
131_ASP GLU ClinVar
chr2:47388887
rs398124648 Pathogenic/Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]; Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
131_ASP GLY ClinVar
chr19:47112212
rs1057523474 Likely pathogenic not provided [MedGen:CN517202]
131_ASP GLU ClinVar
chr19:47112213
rs1064796271 Pathogenic not provided [MedGen:CN517202]
132_GLY GLU ClinVar
chr14:90870835
rs1555366045 Likely pathogenic Long QT syndrome 14 [MedGen:C4015671,OMIM:616247]; Ventricular tachycardia, catecholaminergic polymorphic, 4 [MedGen:C3554047,OMIM:614916]
133_ASP HIS ClinVar
chr2:47388883
rs398124650 Pathogenic/Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]; Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
135_GLN PRO ClinVar
chr2:47388876
rs398124649 Pathogenic/Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]; Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
137_ASN LYS ClinVar
chr2:47388869
rs1553431702 Pathogenic Long QT syndrome 15 [MedGen:C4015695,OMIM:616249]
139_GLU VAL ClinVar
chr14:90870856
rs1064793078 Likely pathogenic not provided [MedGen:CN517202]
140_GLU GLY ClinVar
chr19:47112382
rs1555814427 Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]
141_PHE LEU ClinVar
chr14:90871037
rs199744595 Pathogenic Long QT syndrome 14 [MedGen:C4015671,OMIM:616247]
141_PHE LEU ClinVar
chr14:90871035
rs1085307479 Likely pathogenic not provided [MedGen:CN517202]
144_MET ARG ClinVar
chr2:47387931
- Likely pathogenic Long QT syndrome 1 [MedGen:C4551647,OMIM:192500,SNOMED CT:20852007]