PDB ID 8KME CHAIN2
Protein namePROTEIN (THROMBIN)
Uniprot Accession P00734
The number of similar proteins 256
The number of binding states 15
The number of binding partners 12
Coloring
Unicolor (beige)
The number of binding partners
Group

Downdload
Format:
Molecule viewer
#binding
partners
 >9
  8
  7
  6
  5
  4
  3
  2
  1
  0
Sequence information
1  IVEGSDAEIG   MSPWQVMLFR   KPQELLCGAS   LISDRWVLTA   AHCLLENDLL   50
51  VRIGKHSRTR   YENIEKISML   EKIYIHPRYN   WRNLDRDIAL   MKLKKPVAFS   100
101  DYIHPVCLPD   RETALQAGYK   GRVTGWGNLK   EKGQPSVLQV   VNLPIVERPV   150
151  CKDSTRIRIT   DNMFCAGKPR   GDACEGDSGG   PFVMKSPNRW   YQMGIVSWGE   200
201  GCDDGKYGFY   THVFRLKKWI   QKVIDQFGE                            250
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
32_MET THR VAR_006714 rs121918481 Disease Factor II deficiency (FA2D) [MIM:613679]
37_PRO THR VAR_011782 rs5897 Polymorphism -
67_ARG CYS VAR_006715 rs121918479 Disease Factor II deficiency (FA2D) [MIM:613679]
73_ARG HIS VAR_006716 rs121918482 Disease Factor II deficiency (FA2D) [MIM:613679]
101_ARG TRP VAR_006717 rs121918478 Disease Factor II deficiency (FA2D) [MIM:613679]
146_GLU ALA VAR_006718 - Disease Factor II deficiency (FA2D) [MIM:613679]
164_GLU GLN VAR_068913 - Polymorphism -
226_GLY VAL VAR_006719 rs121918480 Disease Factor II deficiency (FA2D) [MIM:613679]