PDB ID 1AH1 CHAIN A
Protein name CTLA-4
Uniprot Accession P16410
The number of similar proteins 10
The number of binding states 6
The number of binding partners 5
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1AH1 (CHAIN: A)
1 Monomeric state
2 P16410  
3 P33681  
4 P16410   P42081  
5 5GGV   5GGV  
6 P16410   3BX7  
Downdload
 Format:  
Molecule viewer
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partners
  5
  4
  3
  2
  1
  0
Sequence information
1   AMHVAQPAVV   LASSRGIASF   VCEYASPGKA   TEVRVTVLRQ   ADSQVTEVCA   50
51   ATYMMGNELT   FLDDSICTGT   SSGNQVNLTI   QGLRAMDTGL   YICKVELMYP   100
101   PPYYLGIGNG   TQIYVIDPEP   CPDSDQEPK       150
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
3_VAL MET ClinVar
chr2:204735317
rs1553657378 Likely pathogenic Autoimmune lymphoproliferatiVe syndrome, type V [MedGen:C4015214,OMIM:616100,Orphanet:ORPHA436159]
14_ARG TER ClinVar
chr2:204735350
rs606231417 Pathogenic Autoimmune lymphoproliferatiVe syndrome, type V [MedGen:C4015214,OMIM:616100,Orphanet:ORPHA436159]
17_ALA THR ClinVar
chr2:204735359
rs1553657387 Likely pathogenic Autoimmune lymphoproliferatiVe syndrome, type V [MedGen:C4015214,OMIM:616100,Orphanet:ORPHA436159]
33_ARG TRP VAR_072681 rs606231422 Disease Autoimmune lymphoproliferative syndrome 5 (ALPS5) [MIM:616100]
103_PRO THR ClinVar
chr2:204735611
rs1553657430 Pathogenic Autoimmune lymphoproliferatiVe syndrome, type V [MedGen:C4015214,OMIM:616100,Orphanet:ORPHA436159]
105_TYR TER ClinVar
chr2:204735619
rs1357409506 Pathogenic Autoimmune lymphoproliferatiVe syndrome, type V [MedGen:C4015214,OMIM:616100,Orphanet:ORPHA436159]