PDB ID 1AUI     CHAIN B
Protein name SERINE/THREONINE PHOSPHATASE 2B
Uniprot Accession P63098
The number of similar proteins 17
The number of binding states 7
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   GNEASYPLEM   CSHFDADEIK   RLGKRFKKLD   LDNSGSLSVE   EFMSLPELQQ   50
51   NPLVQRVIDI   FDTDGNGEVD   FKEFIEGVSQ   FSVKGDKEQK   LRFAFRIYDM   100
101   DKDGYISNGE   LFQVLKMMVG   NNLKDTQLQQ   IVDKTIINAD   KDGDGRISFE   150
151   EFCAVVGGLD   IHKKMVVDV         200

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
28_LYS ARG 8.3kJPN
chr9:104357118
rs542836480
- 0.0002 -
35_GLY GLU gnomAD
chr9:104357097
rs576097834
- 0.00143383 -
43_MET THR gnomAD
chr9:104357073
rs553900338
- 0.000458613 -
47_GLU LYS gnomAD
chr9:104357062
rs151333989
- 0.00374862 -
47_GLU ALA 8.3kJPN
chr9:104357061
rs1325683448
- - -
47_GLU LYS 8.3kJPN
chr9:104357062
rs151333989
- - -
48_LEU VAL gnomAD
chr9:104357059
rs142403692
- 0.000179233 -
48_LEU PRO 8.3kJPN
chr9:104357058
-
- 0.0002 -
52_PRO LEU 8.3kJPN
chr9:104357046
rs201878659
- 0.0001 -
60_ILE THR 8.3kJPN
chr2:68415684
rs751778712
- 0.0001 -
62_ASP ASN 8.3kJPN
chr9:104357017
rs767514182
- 0.0001 -
65_GLY SER gnomAD
chr9:104357008
rs202237297
- 0.000178958 -
96_SER GLY 8.3kJPN
chr9:104356915
-
- 0.0001 -
110_GLU GLY 8.3kJPN
chr9:104356872
-
- 0.0001 -
129_GLN PRO gnomAD
chr9:104356815
rs771888538
- 0.000270382 -
149_PHE SER 8.3kJPN
chr9:104356755
rs781576089
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.