PDB ID 1D5X     CHAIN B
Protein name HLA CLASS II HISTOCOMPATIBILITY ANTIGEN
Uniprot Accession P13760
The number of similar proteins 129
The number of binding states 20
The number of binding partners 11

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   GDTRPRFLEQ   VKHECHFFNG   TERVRFLDRY   FYHQEEYVRF   DSDVGEYRAV   50
51   TELGRPDAEY   WNSQKDLLEQ   KRAAVDTYCR   HNYGVGESFT   VQRRVYPEVT   100
101   VYPAKTQPLQ   HHNLLVCSVN   GFYPGSIEVR   WFRNGQEEKT   GVVSTGLIQN   150
151   GDWTFQTLVM   LETVPRSGEV   YTCQVEHPSL   TSPLTVEWRA   RS   200

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
1_GLY ARG gnomAD
chr6:32497914
rs76748970
- 0.239628 -
1_GLY VAL 8.3kJPN
chr6:32497913
rs146966122
- 0.0927 -
1_GLY ARG 8.3kJPN
chr6:32497914
rs76748970
- 0.3082 -
1_GLY VAL 8.3kJPN
chr6:32557431
rs761074986
- 0.0696 -
2_ASP ASN gnomAD
chr6:32557429
rs372634318
- 0.000413715 -
2_ASP GLY 8.3kJPN
chr6:32497910
rs139583918
- 0.1119 -
2_ASP GLU 8.3kJPN
chr6:32557427
-
- 0.0001 -
2_ASP GLY 8.3kJPN
chr6:32557428
rs201700261
- 0.1078 -
3_THR PRO 8.3kJPN
chr6:32497908
rs796754225
- 0.0031 -
3_THR PRO 8.3kJPN
chr6:32557426
rs749376442
- 0.0011 -
4_ARG GLY gnomAD
chr6:32557423
rs9256943
- 0.0522666 -
4_ARG GLN 8.3kJPN
chr6:32497904
rs1141741
- 0.1696 -
4_ARG TER 8.3kJPN
chr6:32497905
rs71549219
- - -
4_ARG GLN 8.3kJPN
chr6:32557422
rs17879746
- 0.274 -
5_PRO SER 8.3kJPN
chr6:32557420
rs761045049
- 0.0001 -
6_ARG CYS 8.3kJPN
chr6:32489949
rs1136744
- 0.0124 -
9_GLN ARG gnomAD
chr6:32489939
rs17433849
- 0.000101551 -
9_GLN GLU gnomAD
chr6:32489940
rs1071747
- 0.0301896 -
9_GLN LYS gnomAD
chr6:32489940
rs1071747
- 0.0801815 -
9_TRP GLY gnomAD
chr6:32552144
rs9269959
- 0.0278498 -
9_GLN ARG 8.3kJPN
chr6:32489939
rs17433849
- 0.0033 -
9_GLN TER 8.3kJPN
chr6:32489940
rs1071747
- - -
9_TRP TER 8.3kJPN
chr6:32552143
rs9269958
- 0.5107 -
9_TRP GLY 8.3kJPN
chr6:32552144
rs9269959
- 0.4539 -
10_GLN LEU gnomAD
chr6:32489936
rs201948867
- 0.00139793 -
10_GLN LEU gnomAD
chr6:32552140
rs17882663
- 0.0184337 -
10_GLN LEU 8.3kJPN
chr6:32489936
rs201948867
- 0.0661 -
10_GLN GLU 8.3kJPN
chr6:32489937
rs200071340
- 0.0083 -
10_GLN LEU 8.3kJPN
chr6:32552140
rs17882663
- 0.1363 -
11_ASP VAL gnomAD
chr6:32489933
rs1071748
- 0.00220524 -
11_ASP GLY gnomAD
chr6:32489933
rs1071748
- 0.000232851 -
11_ASP HIS gnomAD
chr6:32489934
rs1136752
- 0.00218949 -
11_PRO LEU gnomAD
chr6:32552137
rs17878703
- 0.0263411 -
11_PRO ARG gnomAD
chr6:32552137
rs17878703
- 0.000573792 -
11_PRO ALA gnomAD
chr6:32552138
rs9269955
- 0.00589531 -
11_ASP VAL 8.3kJPN
chr6:32489933
rs1071748
- - -
11_ASP HIS 8.3kJPN
chr6:32489934
rs1136752
- 0.0698 -
11_PRO LEU 8.3kJPN
chr6:32552137
rs17878703
- - -
11_PRO SER 8.3kJPN
chr6:32552138
rs9269955
- - -
12_LYS THR gnomAD
chr6:32489930
rs200581589
- 0.0371716 -
12_LYS THR gnomAD
chr6:32552134
rs1136756
- 0.186264 -
12_LYS THR 8.3kJPN
chr6:32489930
rs200581589
- 0.0239 -
12_LYS THR 8.3kJPN
chr6:32552134
rs1136756
- 0.293 -
12_LYS TER 8.3kJPN
chr6:32552135
rs766505678
- 0.0011 -
13_TYR PHE gnomAD
chr6:32489927
rs1136760
- 0.0732127 -
13_TYR SER gnomAD
chr6:32489927
rs1136760
- 0.0473745 -
13_TYR HIS gnomAD
chr6:32489928
rs1136757
- 0.000154771 -
13_ARG SER gnomAD
chr6:32552130
rs9269951
- 0.293707 -
13_ARG MET gnomAD
chr6:32552131
rs1136759
- 0.00891459 -
13_ARG THR gnomAD
chr6:32552131
rs1136759
- 0.229957 -
13_ARG LYS gnomAD
chr6:32552131
rs1136759
- 0.000120467 -
13_ARG TRP gnomAD
chr6:32552132
rs1136758
- 0.247761 -
13_ARG GLY gnomAD
chr6:32552132
rs1136758
- 0.0272216 -
13_TYR PHE 8.3kJPN
chr6:32489927
rs1136760
- - -
13_TYR HIS 8.3kJPN
chr6:32489928
rs1136757
- 0.2337 -
13_ARG SER 8.3kJPN
chr6:32552130
rs9269951
- 0.7669 -
13_ARG MET 8.3kJPN
chr6:32552131
rs1136759
- - -
13_ARG TRP 8.3kJPN
chr6:32552132
rs1136758
- - -
14_GLU LYS 8.3kJPN
chr6:32489925
rs17405212
- 0.0027 -
16_HIS TYR gnomAD
chr6:32489919
rs199680107
- 0.0125183 -
16_HIS GLN gnomAD
chr6:32552121
rs17879981
- 0.000590411 -
16_HIS TYR gnomAD
chr6:32552123
rs17879702
- 0.031714 -
16_HIS TYR 8.3kJPN
chr6:32489919
rs199680107
- 0.0061 -
16_HIS GLN 8.3kJPN
chr6:32552121
rs17879981
- 0.0187 -
16_HIS TYR 8.3kJPN
chr6:32552123
rs17879702
- 0.1645 -
18_PHE LEU gnomAD
chr6:32552117
rs114435757
- 0.00153931 -
18_PHE LEU 8.3kJPN
chr6:32489913
rs201628145
- 0.0676 -
18_PHE TYR 8.3kJPN
chr6:32552116
-
- 0.0001 -
18_PHE LEU 8.3kJPN
chr6:32552117
rs114435757
- 0.2573 -
22_GLU GLN 8.3kJPN
chr6:32552105
-
- 0.0001 -
23_ARG LEU 8.3kJPN
chr6:32552101
-
- 0.0001 -
24_VAL GLU 8.3kJPN
chr6:32552098
rs1335931724
- 0.0008 -
25_ARG GLN gnomAD
chr6:32552095
rs17885382
- 0.000191237 -
25_ARG GLN 8.3kJPN
chr6:32489891
rs112906420
- 0.0012 -
25_ARG TRP 8.3kJPN
chr6:32489892
rs184278615
- 0.0838 -
25_ARG GLN 8.3kJPN
chr6:32552095
rs17885382
- 0.0014 -
25_ARG TRP 8.3kJPN
chr6:32552096
rs188617679
- 0.2577 -
26_PHE LEU gnomAD
chr6:32489887
rs202197820
- 0.000648374 -
26_PHE LEU gnomAD
chr6:32489887
rs202197820
- 0.00119301 -
26_PHE TYR gnomAD
chr6:32489888
rs147440497
- 0.0457758 -
26_PHE LEU gnomAD
chr6:32552091
rs1059572
- 0.0106895 -
26_PHE TYR gnomAD
chr6:32552092
rs1059569
- 0.131883 -
26_PHE ILE gnomAD
chr6:32552093
rs201128876
- 0.00153433 -
26_PHE TYR 8.3kJPN
chr6:32489888
rs147440497
- 0.3205 -
26_PHE ILE 8.3kJPN
chr6:32489889
rs201469165
- 0.0856 -
26_PHE LEU 8.3kJPN
chr6:32552091
rs1059572
- - -
26_PHE TYR 8.3kJPN
chr6:32552092
rs1059569
- 0.3616 -
26_PHE ILE 8.3kJPN
chr6:32552093
rs201128876
- 0.2045 -
28_HIS GLN gnomAD
chr6:32489881
rs202185589
- 0.000211982 -
28_HIS GLN gnomAD
chr6:32489881
rs202185589
- 0.00071544 -
28_HIS ASP gnomAD
chr6:32489883
rs142793258
- 0.0371285 -
28_ASP GLU gnomAD
chr6:32552085
rs1059575
- 0.0502833 -
28_ASP GLU gnomAD
chr6:32552085
rs1059575
- 0.0718385 -
28_ASP VAL gnomAD
chr6:32552086
rs200532329
- 0.00159896 -
28_ASP TYR gnomAD
chr6:32552087
rs17878947
- 0.0505099 -
28_ASP ASN gnomAD
chr6:32552087
rs17878947
- 0.00163787 -
28_HIS GLN 8.3kJPN
chr6:32489881
rs202185589
- - -
28_HIS LEU 8.3kJPN
chr6:32489882
rs200298678
- 0.0902 -
28_HIS TYR 8.3kJPN
chr6:32489883
rs142793258
- - -
28_ASP GLU 8.3kJPN
chr6:32552085
rs1059575
- - -
28_ASP VAL 8.3kJPN
chr6:32552086
rs200532329
- 0.2569 -
28_ASP TYR 8.3kJPN
chr6:32552087
rs17878947
- - -
30_ASP GLY gnomAD
chr6:32489876
rs41546317
- 0.273379 -
30_ASP TYR gnomAD
chr6:32489877
rs138849995
- 0.0248491 -
30_ASP HIS gnomAD
chr6:32489877
rs138849995
- 0.000192949 -
30_TYR PHE gnomAD
chr6:32552080
rs3175105
- 0.000143563 -
30_TYR CYS gnomAD
chr6:32552080
rs3175105
- 0.0114161 -
30_TYR HIS gnomAD
chr6:32552081
rs11554462
- 0.0164392 -
30_ASP VAL 8.3kJPN
chr6:32489876
rs41546317
- - -
30_ASP TYR 8.3kJPN
chr6:32489877
rs138849995
- - -
30_TYR PHE 8.3kJPN
chr6:32552080
rs3175105
- - -
30_TYR HIS 8.3kJPN
chr6:32552081
rs11554462
- 0.1285 -
31_ILE PHE gnomAD
chr6:32489874
rs140781802
- 0.0253416 -
31_ILE VAL gnomAD
chr6:32489874
rs140781802
- 0.000165271 -
31_PHE ILE gnomAD
chr6:32552078
rs17882300
- 0.0234445 -
31_ILE PHE 8.3kJPN
chr6:32489874
rs140781802
- - -
31_PHE ILE 8.3kJPN
chr6:32552078
rs17882300
- - -
32_TYR HIS gnomAD
chr6:32489871
rs137863146
- 0.0159466 -
32_TYR HIS gnomAD
chr6:32552075
rs1064664
- 0.256396 -
32_TYR HIS 8.3kJPN
chr6:32489871
rs137863146
- 0.0664 -
32_TYR HIS 8.3kJPN
chr6:32552075
rs1064664
- 0.2465 -
33_ASN HIS gnomAD
chr6:32489868
rs1059576
- 0.000671158 -
33_ASN HIS gnomAD
chr6:32552072
rs17879995
- 0.115207 -
33_ASN HIS 8.3kJPN
chr6:32489868
rs1059576
- 0.1914 -
33_ASN THR 8.3kJPN
chr6:32552071
-
- 0.0001 -
33_ASN HIS 8.3kJPN
chr6:32552072
rs17879995
- 0.1318 -
37_ASP VAL gnomAD
chr6:32489855
rs200042906
- 0.00121985 -
37_ASP ALA gnomAD
chr6:32489855
rs200042906
- 0.00592497 -
37_ASP TYR gnomAD
chr6:32489856
rs707956
- 0.086144 -
37_ASP ASN gnomAD
chr6:32489856
rs707956
- 0.262709 -
37_SER PHE gnomAD
chr6:32552059
rs707957
- 0.0795254 -
37_SER TYR gnomAD
chr6:32552059
rs707957
- 0.568406 -
37_SER THR gnomAD
chr6:32552060
rs16822820
- 0.194034 -
37_ASP GLU 8.3kJPN
chr6:32489854
rs770407170
- 0.0007 -
37_ASP VAL 8.3kJPN
chr6:32489855
rs200042906
- - -
37_ASP TYR 8.3kJPN
chr6:32489856
rs707956
- - -
37_SER PHE 8.3kJPN
chr6:32552059
rs707957
- - -
37_SER THR 8.3kJPN
chr6:32552060
rs16822820
- 0.0921 -
38_LEU SER gnomAD
chr6:32489852
rs192498095
- 0.010882 -
38_LEU VAL gnomAD
chr6:32489853
rs1059580
- 0.379601 -
38_VAL ALA gnomAD
chr6:32552056
rs17878951
- 0.00251768 -
38_VAL LEU gnomAD
chr6:32552057
rs17878614
- 0.00358455 -
38_LEU SER 8.3kJPN
chr6:32489852
rs192498095
- 0.1272 -
38_VAL ALA 8.3kJPN
chr6:32552056
rs17878951
- 0.3105 -
38_VAL LEU 8.3kJPN
chr6:32552057
rs17878614
- 0.057 -
39_ARG GLY 8.3kJPN
chr6:32552054
rs754953589
- 0.0001 -
40_PHE TYR gnomAD
chr6:32489846
rs150479833
- 0.00188581 -
40_PHE TYR 8.3kJPN
chr6:32489846
rs150479833
- 0.0976 -
40_PHE TYR 8.3kJPN
chr6:32552050
rs17882455
- 0.255 -
40_PHE VAL 8.3kJPN
chr6:32552051
-
- 0.0001 -
41_ASP ASN gnomAD
chr6:32489844
rs140580884
- 0.000470975 -
41_ASP ASN 8.3kJPN
chr6:32489844
rs140580884
- 0.0939 -
41_ASP ASN 8.3kJPN
chr6:32552048
rs56158521
- 0.3257 -
42_SER GLY 8.3kJPN
chr6:32489841
-
- 0.0001 -
44_VAL LEU gnomAD
chr6:32489835
rs118111025
- 0.0275528 -
44_VAL LEU gnomAD
chr6:32552039
rs150747106
- 0.00175038 -
44_VAL MET gnomAD
chr6:32552039
rs150747106
- 0.147503 -
44_VAL MET 8.3kJPN
chr6:32489835
rs118111025
- - -
44_VAL MET 8.3kJPN
chr6:32552039
rs150747106
- - -
45_GLY ARG 8.3kJPN
chr6:32552036
rs17885437
- 0.0001 -
47_TYR PHE gnomAD
chr6:32489825
rs148834340
- 0.0977658 -
47_PHE TYR gnomAD
chr6:32552029
rs17884945
- 0.314464 -
47_TYR PHE 8.3kJPN
chr6:32489825
rs148834340
- 0.0443 -
47_PHE TYR 8.3kJPN
chr6:32552029
rs17884945
- 0.5244 -
48_ARG GLN gnomAD
chr6:32489822
rs115417906
- 0.0289843 -
48_ARG GLN 8.3kJPN
chr6:32489822
rs115417906
- 0.0773 -
48_ARG GLN 8.3kJPN
chr6:32552026
rs17886436
- 0.2556 -
50_VAL ALA gnomAD
chr6:32552020
rs17885908
- 0.00264425 -
51_THR ARG gnomAD
chr6:32489813
rs79606458
- 0.0176113 -
51_THR ARG gnomAD
chr6:32552017
rs1059582
- 0.000126062 -
51_THR ARG 8.3kJPN
chr6:32489813
rs79606458
- 0.0196 -
51_THR ARG 8.3kJPN
chr6:32552017
rs1059582
- 0.0609 -
52_GLU VAL ClinVar
chr6:32552014
-
Pathogenic - Pulmonary artery atresia [Human Phenotype Ontology:HP:0004935,MedGen:C0265908]
57_ASP VAL gnomAD
chr6:32489795
rs144532965
- 0.0113368 -
57_ASP GLY gnomAD
chr6:32489795
rs144532965
- 0.0395773 -
57_ASP ALA gnomAD
chr6:32489795
rs144532965
- 0.000118267 -
57_ASP ASN gnomAD
chr6:32489796
rs145586726
- 0.0350737 -
57_ASP VAL gnomAD
chr6:32551999
rs17885129
- 0.00835667 -
57_ASP GLY gnomAD
chr6:32551999
rs17885129
- 0.00650247 -
57_ASP ALA gnomAD
chr6:32551999
rs17885129
- 0.00835028 -
57_ASP ASN gnomAD
chr6:32552000
rs17880292
- 0.00566168 -
57_ASP VAL 8.3kJPN
chr6:32489795
rs144532965
- - -
57_ASP ASN 8.3kJPN
chr6:32489796
rs145586726
- 0.1956 -
57_ASP VAL 8.3kJPN
chr6:32551999
rs17885129
- - -
57_ASP ASN 8.3kJPN
chr6:32552000
rs17880292
- 0.123 -
58_ALA ASP gnomAD
chr6:32489792
rs41562816
- 0.113137 -
58_ALA ASP gnomAD
chr6:32551996
rs1059584
- 0.0098369 -
58_ALA ASP 8.3kJPN
chr6:32489792
rs41562816
- 0.0246 -
58_ALA ASP 8.3kJPN
chr6:32551996
rs1059584
- 0.0026 -
60_TYR SER gnomAD
chr6:32489786
rs41541218
- 0.012153 -
60_TYR SER gnomAD
chr6:32551990
rs1059586
- 0.00564727 -
60_TYR HIS gnomAD
chr6:32551991
rs17882583
- 0.007458 -
60_TYR SER 8.3kJPN
chr6:32489786
rs41541218
- 0.1506 -
60_TYR HIS 8.3kJPN
chr6:32489787
rs746070999
- - -
60_TYR SER 8.3kJPN
chr6:32551990
rs1059586
- 0.1099 -
60_TYR HIS 8.3kJPN
chr6:32551991
rs17882583
- 0.0417 -
61_TRP ARG 8.3kJPN
chr6:32551988
-
- 0.0001 -
67_PHE LEU gnomAD
chr6:32489766
rs696318
- 0.0565996 -
67_PHE ILE gnomAD
chr6:32489766
rs696318
- 0.0461624 -
67_ILE PHE gnomAD
chr6:32551970
rs17886918
- 0.00867543 -
67_ILE LEU gnomAD
chr6:32551970
rs17886918
- 0.201872 -
67_PHE ILE 8.3kJPN
chr6:32489766
rs696318
- - -
67_ILE PHE 8.3kJPN
chr6:32551970
rs17886918
- - -
69_GLU ALA 8.3kJPN
chr6:32489759
rs764618537
- 0.0004 -
69_GLU TER 8.3kJPN
chr6:32551964
-
- 0.0001 -
70_ASP GLU gnomAD
chr6:32489755
rs41559913
- 0.00041613 -
70_ASP GLU 8.3kJPN
chr6:32489755
rs41559913
- 0.0013 -
71_ARG THR gnomAD
chr6:32489753
rs41544215
- 0.00199454 -
71_ARG LYS gnomAD
chr6:32489753
rs41544215
- 0.0548634 -
71_ARG GLY gnomAD
chr6:32489754
rs41551116
- 0.0377136 -
71_ALA GLY gnomAD
chr6:32551957
rs9269942
- 0.191881 -
71_ALA GLU gnomAD
chr6:32551957
rs9269942
- 0.0233567 -
71_ALA THR gnomAD
chr6:32551958
rs1064592
- 0.352483 -
71_ARG SER 8.3kJPN
chr6:32489752
rs143737208
- 0.0003 -
71_ARG LYS 8.3kJPN
chr6:32489753
rs41544215
- 0.0291 -
71_ARG GLY 8.3kJPN
chr6:32489754
rs41551116
- 0.0588 -
71_ALA GLU 8.3kJPN
chr6:32551957
rs9269942
- - -
71_ALA THR 8.3kJPN
chr6:32551958
rs1064592
- 0.3453 -
72_ARG GLY 8.3kJPN
chr6:32489751
rs149410716
- 0.0003 -
72_ARG TRP 8.3kJPN
chr6:32551955
rs17885222
- 0.0016 -
74_ALA VAL gnomAD
chr6:32489744
rs1059598
- 0.0855483 -
74_ALA GLU gnomAD
chr6:32489744
rs1059598
- 0.00996973 -
74_ALA PRO gnomAD
chr6:32489745
rs41548618
- 0.0829852 -
74_ALA VAL gnomAD
chr6:32551948
rs17886882
- 0.000898266 -
74_ALA GLU gnomAD
chr6:32551948
rs17886882
- 0.118064 -
74_ALA PRO gnomAD
chr6:32551949
rs16822805
- 0.000608804 -
74_ALA THR gnomAD
chr6:32551949
rs16822805
- 0.00761005 -
74_ALA VAL 8.3kJPN
chr6:32489744
rs1059598
- - -
74_ALA THR 8.3kJPN
chr6:32489745
rs41548618
- - -
74_ALA VAL 8.3kJPN
chr6:32551948
rs17886882
- - -
74_ALA THR 8.3kJPN
chr6:32551949
rs16822805
- - -
76_ASP GLY 8.3kJPN
chr6:32489738
rs776845219
- 0.0005 -
76_ASP GLY 8.3kJPN
chr6:32551942
rs767943289
- 0.0107 -
77_THR ASN gnomAD
chr6:32489735
rs115817940
- 0.00716526 -
77_THR ASN gnomAD
chr6:32551939
rs9269941
- 0.0159839 -
77_THR ASN 8.3kJPN
chr6:32489735
rs115817940
- 0.1034 -
77_THR ASN 8.3kJPN
chr6:32551939
rs9269941
- 0.1856 -
78_TYR PHE gnomAD
chr6:32489732
rs1064677
- 0.00221315 -
78_TYR ASP gnomAD
chr6:32489733
rs1064595
- 0.00223623 -
78_TYR PHE 8.3kJPN
chr6:32489732
rs1064677
- 0.0872 -
78_TYR ASP 8.3kJPN
chr6:32489733
rs1064595
- 0.0873 -
78_TYR PHE 8.3kJPN
chr6:32551936
rs17879620
- - -
78_TYR ASP 8.3kJPN
chr6:32551937
rs17884043
- 0.0002 -
80_ARG LYS 8.3kJPN
chr6:32489726
-
- 0.0001 -
81_HIS TYR gnomAD
chr6:32489724
rs142908883
- 0.00047137 -
81_HIS TYR gnomAD
chr6:32551928
rs29029549
- 0.0450279 -
81_HIS TYR 8.3kJPN
chr6:32489724
rs142908883
- 0.0154 -
81_HIS ARG 8.3kJPN
chr6:32551927
-
- 0.0001 -
81_HIS TYR 8.3kJPN
chr6:32551928
rs29029549
- - -
85_VAL ALA gnomAD
chr6:32551915
rs17424145
- 0.0203139 -
85_VAL ALA 8.3kJPN
chr6:32489711
rs1136778
- 0.0108 -
85_VAL ALA 8.3kJPN
chr6:32551915
rs17424145
- 0.0444 -
86_VAL GLY gnomAD
chr6:32551912
rs17885482
- 0.0854845 -
86_GLY VAL 8.3kJPN
chr6:32489708
rs41556512
- 0.0228 -
86_VAL GLY 8.3kJPN
chr6:32551912
rs17885482
- 0.2507 -
89_PHE LEU 8.3kJPN
chr6:32489700
-
- 0.0001 -
96_GLU ASP gnomAD
chr6:32487424
rs141474277
- 0.00907456 -
96_GLN HIS gnomAD
chr6:32549611
rs1071752
- 0.501137 -
96_GLU ASP 8.3kJPN
chr6:32487424
rs141474277
- - -
96_GLU TER 8.3kJPN
chr6:32487426
rs1071751
- - -
96_GLN HIS 8.3kJPN
chr6:32549611
rs1071752
- - -
96_GLN TER 8.3kJPN
chr6:32549613
rs17882084
- - -
98_LYS GLU gnomAD
chr6:32487420
rs138786370
- 0.0369287 -
98_LYS GLN gnomAD
chr6:32487420
rs138786370
- 0.014728 -
98_LYS GLU gnomAD
chr6:32549607
rs17405219
- 0.00318656 -
98_LYS GLN gnomAD
chr6:32549607
rs17405219
- 0.0903753 -
98_LYS GLN 8.3kJPN
chr6:32487420
rs138786370
- - -
98_LYS GLN 8.3kJPN
chr6:32549607
rs17405219
- - -
102_TYR CYS 8.3kJPN
chr6:32549594
rs1195941088
- 0.0001 -
104_ALA VAL gnomAD
chr6:32487401
rs758743151
- 0.000169048 -
104_ALA SER gnomAD
chr6:32487402
rs114131132
- 0.144843 -
104_ALA VAL 8.3kJPN
chr6:32487401
rs758743151
- 0.014 -
104_ALA SER 8.3kJPN
chr6:32487402
rs114131132
- 0.0271 -
104_SER LEU 8.3kJPN
chr6:32549588
rs201929247
- 0.2775 -
104_SER ALA 8.3kJPN
chr6:32549589
rs2308760
- 0.3891 -
105_ARG LYS gnomAD
chr6:32487398
rs115198947
- 0.378218 -
105_ARG LYS 8.3kJPN
chr6:32487398
rs115198947
- 0.5764 -
120_ASN SER gnomAD
chr6:32487353
rs114293611
- 0.126415 -
120_ASN SER 8.3kJPN
chr6:32487353
rs114293611
- 0.3118 -
120_SER ASN 8.3kJPN
chr6:32549540
rs1059351
- 0.2977 -
123_TYR CYS 8.3kJPN
chr6:32487344
rs201863832
- 0.1009 -
123_TYR CYS 8.3kJPN
chr6:32549531
rs112796209
- 0.2949 -
125_GLY ALA gnomAD
chr6:32549525
rs16822698
- 0.113657 -
125_GLY ALA 8.3kJPN
chr6:32487338
rs113395425
- 0.1018 -
125_GLY ALA 8.3kJPN
chr6:32549525
rs16822698
- 0.2962 -
127_ILE VAL gnomAD
chr6:32549520
rs202047044
- 0.00606299 -
127_ILE VAL 8.3kJPN
chr6:32487333
rs199986849
- 0.1025 -
127_ILE VAL 8.3kJPN
chr6:32549520
rs202047044
- 0.2104 -
133_LEU ARG gnomAD
chr6:32549501
rs707954
- 0.655748 -
133_LEU GLN gnomAD
chr6:32549501
rs707954
- 0.198249 -
133_ARG GLN 8.3kJPN
chr6:32487314
rs201882312
- 0.1743 -
133_LEU GLN 8.3kJPN
chr6:32549501
rs707954
- - -
135_SER GLY gnomAD
chr6:32487309
rs1059633
- 0.773043 -
135_GLY SER gnomAD
chr6:32549496
rs757966595
- 0.00286634 -
135_SER GLY 8.3kJPN
chr6:32487309
rs1059633
- 0.7151 -
138_GLU LYS gnomAD
chr6:32487300
rs141514736
- 0.000149782 -
140_ALA THR gnomAD
chr6:32487294
rs75709987
- 0.28998 -
140_ALA THR 8.3kJPN
chr6:32487294
rs75709987
- 0.2776 -
140_ALA THR 8.3kJPN
chr6:32549481
rs78916069
- 0.3391 -
141_GLY VAL 8.3kJPN
chr6:32549477
-
- 0.0001 -
142_MET VAL gnomAD
chr6:32549475
rs701829
- 0.863959 -
142_MET VAL 8.3kJPN
chr6:32549475
rs701829
- 0.8131 -
149_GLN HIS gnomAD
chr6:32487265
rs139485758
- 0.00403901 -
149_GLN HIS gnomAD
chr6:32487265
rs139485758
- 0.0667887 -
149_GLN HIS 8.3kJPN
chr6:32487265
rs139485758
- - -
149_GLN HIS 8.3kJPN
chr6:32549452
rs77637983
- - -
153_TRP TER 8.3kJPN
chr6:32549441
-
- 0.0001 -
157_THR ILE gnomAD
chr6:32487242
rs41559420
- 0.0298228 -
157_THR ILE 8.3kJPN
chr6:32487242
rs41559420
- 0.0111 -
159_VAL MET gnomAD
chr6:32549424
rs112116022
- 0.0380135 -
159_VAL MET 8.3kJPN
chr6:32487237
rs192264100
- 0.1504 -
159_VAL MET 8.3kJPN
chr6:32549424
rs112116022
- 0.2358 -
166_ARG GLN gnomAD
chr6:32487215
rs148933006
- 0.0158838 -
166_ARG GLN gnomAD
chr6:32549402
rs3205588
- 0.0738165 -
166_ARG GLN 8.3kJPN
chr6:32487215
rs148933006
- 0.0508 -
166_ARG GLN 8.3kJPN
chr6:32549402
rs3205588
- 0.1624 -
168_GLY ALA 8.3kJPN
chr6:32487209
rs189435670
- 0.2772 -
168_GLY ALA 8.3kJPN
chr6:32549396
rs2308775
- 0.1814 -
172_THR SER 8.3kJPN
chr6:32549385
-
- 0.0001 -
175_VAL LEU 8.3kJPN
chr6:32487189
rs201575183
- 0.2812 -
175_VAL LEU 8.3kJPN
chr6:32549376
rs36044702
- 0.1709 -
176_GLU LYS 8.3kJPN
chr6:32487186
rs772100213
- 0.0002 -
180_VAL LEU gnomAD
chr6:32487174
rs112872773
- 0.186502 -
180_VAL MET gnomAD
chr6:32487174
rs112872773
- 0.0185597 -
180_VAL LEU gnomAD
chr6:32549361
rs111739605
- 0.000737479 -
180_VAL MET gnomAD
chr6:32549361
rs111739605
- 0.130972 -
180_VAL MET 8.3kJPN
chr6:32487174
rs112872773
- - -
180_VAL MET 8.3kJPN
chr6:32549361
rs111739605
- - -
181_THR MET gnomAD
chr6:32487170
rs1136633
- 0.170325 -
181_THR ILE gnomAD
chr6:32549357
rs200809587
- 0.147837 -
181_THR MET 8.3kJPN
chr6:32487170
rs1136633
- 0.3647 -
181_THR ILE 8.3kJPN
chr6:32549357
rs200809587
- 0.3785 -
182_SER ARG 8.3kJPN
chr6:32487166
-
- 0.0002 -
182_SER ARG 8.3kJPN
chr6:32549353
-
- 0.0002 -
183_PRO ALA gnomAD
chr6:32487165
rs142204283
- 0.0631835 -
183_PRO ALA gnomAD
chr6:32549352
rs1136846
- 0.00757603 -
183_PRO LEU 8.3kJPN
chr6:32487164
rs111541713
- 0.2886 -
183_PRO ALA 8.3kJPN
chr6:32487165
rs142204283
- 0.0255 -
183_PRO LEU 8.3kJPN
chr6:32549351
rs17885501
- 0.1569 -
183_PRO ALA 8.3kJPN
chr6:32549352
rs1136846
- 0.0469 -
185_THR ILE 8.3kJPN
chr6:32549345
rs752658977
- 0.0002 -
187_GLU GLN gnomAD
chr6:32549340
rs33936261
- 0.128889 -
187_GLU GLN 8.3kJPN
chr6:32487153
rs112024745
- 0.0853 -
187_GLU GLN 8.3kJPN
chr6:32549340
rs33936261
- 0.3103 -
189_ARG SER 8.3kJPN
chr6:32548632
rs1136881
- 0.2322 -
189_ARG GLY 8.3kJPN
chr6:32549334
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.