PDB ID 1EFH     CHAIN A
Protein name HYDROXYSTEROID SULFOTRANSFERASE
Uniprot Accession Q06520
The number of similar proteins 10
The number of binding states 2
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1EFH (CHAIN: A)
1 Q06520  
2 Monomeric state

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   MSDDFLWFEG   IAFPTMGFRS   ETLRKVRDEF   VIRDEDVIIL   TYPKSGTNWL   50
51   AEILCLMHSK   GDAKWIQSVP   IWERSPWVES   EIGYTALSET   ESPRLFSSHL   100
101   PIQLFPKSFF   SSKAKVIYLM   RNPRDVLVSG   YFFWKNMKFI   KKPKSWEEYF   150
151   EWFCQGTVLY   GSWFDHIHGW   MPMREEKNFL   LLSYEELKQD   TGRTIEKICQ   200
201   FLGKTLEPEE   LNLILKNSSF   QSMKENKMSN   YSLLSVDYVV   DKAQLLRKGV   250
251   SGDWKNHFTV   AQAEDFDKLF   QEKMADLPRK   LAAALEHHHH   HH   300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
4_ASP ASN 8.3kJPN
chr19:48389505 		rs750713459
- 0.0001 -
9_GLU TER 8.3kJPN
chr19:48389490 		-
- 0.0001 -
31_VAL MET 8.3kJPN
chr19:48389424 		rs1224724913
- 0.0001 -
38_ILE VAL 8.3kJPN
chr19:48389403 		-
- 0.0001 -
44_LYS GLU VAR_083881 rs772897551
LB/B - -
46_GLY GLU 8.3kJPN
chr19:48387042 		-
- 0.0001 -
63_ALA PRO VAR_052520 rs11569681
LB/B - -
63_ALA PRO gnomAD
chr19:48386992 		rs11569681
- 0.00474414 -
73_GLU GLY gnomAD
chr19:48386961 		rs761528504
- 0.000294263 -
74_ARG TER 8.3kJPN
chr19:48386959 		rs62529832
- 0.0013 -
76_PRO THR VAR_083882 rs775030275
LB/B - -
111_SER GLY gnomAD
chr19:48386848 		rs186827680
- 0.000278379 -
147_GLU LYS VAR_083883 rs751309613
LB/B - -
148_GLU LYS VAR_083884 rs368067020
LB/B - -
152_TRP GLY gnomAD
chr19:48385359 		rs139437036
- 0.000266911 -
184_TYR ASP 8.3kJPN
chr19:48382310 		-
- 0.0001 -
209_GLU LYS 8.3kJPN
chr19:48378034 		rs370526585
- 0.0001 -
227_LYS GLU gnomAD
chr19:48377980 		rs11569680
- 0.000564756 -
230_ASN ILE gnomAD
chr19:48377970 		rs148329743
- 0.000477259 -
245_LEU PHE gnomAD
chr19:48377926 		rs190776413
- 0.000188623 -
245_LEU PHE 8.3kJPN
chr19:48377926 		rs190776413
- 0.0049 -
246_LEU PRO VAR_083885 rs757338859
LB/B - -
258_PHE LEU VAR_083886 rs746239667
LB/B - -
261_ALA THR VAR_052521 rs11569679
LB/B - -
261_ALA THR gnomAD
chr19:48374789 		rs11569679
- 0.00928156 -
262_GLN GLU VAR_083887 rs753928755
LB/B - -
264_GLU ALA 8.3kJPN
chr19:48374779 		rs754922906
- 0.0009 -
(Powered by wupsivus)

Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.