PDB ID 1EH7 CHAIN A
Protein name O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
Uniprot Accession P16455
The number of similar proteins 7
The number of binding states 1
The number of binding partners 0
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
1EH7 (CHAIN: A)
1 Monomeric state
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partners
  0
Sequence information
1   MDKDCEMKRT   TLDSPLGKLE   LSGCEQGLHE   IKLLGKGTSA   ADAVEVPAPA   50
51   AVLGGPEPLM   QCTAWLNAYF   HQPEAIEEFP   VPALHHPVFQ   QESFTRQVLW   100
101   KLLKVVKFGE   VISYQQLAAL   AGNPKAARAV   GGAMRGNPVP   ILIPXHRVVC   150
151   SSGAVGNYSG   GLAVKEWLLA   HEGHRLGKPG   LGGSSGLAGA   WLKGAGATSG   200
201   SPPAGRN           250
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
30_GLU LYS VAR_014750 rs2020893 Polymorphism -
53_LEU PHE VAR_056129 rs12917 Polymorphism -
58_PRO SER VAR_029112 rs2308322 Polymorphism -
65_TRP CYS VAR_020354 rs2282164 Polymorphism -
84_LEU PHE VAR_014751 rs12917 Polymorphism -
112_ILE VAL VAR_056130 rs2308321 Polymorphism -
143_ILE VAL VAR_014752 rs2308321 Polymorphism -
160_GLY ARG VAR_014753 rs2308318 Polymorphism -
166_GLU ASP VAR_014754 rs2308320 Polymorphism -