PDB ID 1NE7     CHAIN A
Protein name Glucosamine-6-phosphate isomerase
Uniprot Accession P46926
The number of similar proteins 6
The number of binding states 1
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1NE7 (CHAIN: A)
1 P46926   P46926   P46926   P46926  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   MKLIILEHYS   QASEWAAKYI   RNRIIQFNPG   PEKYFTLGLP   TGSTPLGCYK   50
51   KLIEYYKNGD   LSFKYVKTFN   MDEYVGLPRD   HPESYHSFMW   NNFFKHIDIH   100
101   PENTHILDGN   AVDLQAECDA   FEEKIKAAGG   IELFVGGIGP   DGHIAFNEPG   150
151   SSLVSRTRVK   TLAMDTILAN   ARFFDGELTK   VPTMALTVGV   GTVMDAREVM   200
201   ILITGAHKAF   ALYKAIEEGV   NHMWTVSAFQ   QHPRTVFVCD   EDATLELKVK   250
251   TVKYFKGLML   VHNKLVDPLY   SIKEKETEKS   QSSKKPYSD     300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
2_LYS ASN 8.3kJPN
chr5:141391595 		-
- 0.0001 -
3_LEU PRO 8.3kJPN
chr5:141391593 		-
- 0.0001 -
23_ARG CYS gnomAD
chr4:44724158 		rs145396953
- 0.00385335 -
23_ARG CYS 8.3kJPN
chr4:44724158 		rs145396953
- 0.0014 -
31_GLN GLU 8.3kJPN
chr4:44724134 		-
- 0.0001 -
48_CYS TRP 8.3kJPN
chr4:44720408 		rs749306588
- 0.0002 -
59_GLY ALA 8.3kJPN
chr5:141387414 		-
- 0.0001 -
67_LYS MET 8.3kJPN
chr4:44720352 		rs1287344575
- 0.0001 -
67_LYS GLU 8.3kJPN
chr4:44720353 		rs1330142987
- 0.0001 -
82_PRO LEU 8.3kJPN
chr5:141385873 		rs759334566
- 0.0001 -
92_ASN HIS 8.3kJPN
chr4:44719265 		-
- 0.0002 -
96_HIS ARG 8.3kJPN
chr5:141385831 		rs779438309
- 0.0001 -
97_ILE VAL 8.3kJPN
chr4:44719250 		-
- 0.0005 -
113_ASP TYR 8.3kJPN
chr4:44719202 		rs553245173
- 0.0001 -
127_ALA THR gnomAD
chr5:141385739 		rs200971161
- 0.000127315 -
159_LEU ILE 8.3kJPN
chr4:44713089 		rs749581413
- 0.0001 -
171_ALA VAL 8.3kJPN
chr5:141384579 		-
- 0.0001 -
177_ASP ASN 8.3kJPN
chr4:44713035 		rs1414508671
- 0.0004 -
189_GLY VAL gnomAD
chr5:141384525 		rs146216672
- 0.00017172 -
198_GLU TER 8.3kJPN
chr5:141384499 		rs752006328
- 0.0001 -
226_VAL ALA 8.3kJPN
chr4:44709861 		-
- 0.0001 -
227_SER CYS 8.3kJPN
chr4:44709858 		rs749014155
- 0.0003 -
233_PRO SER 8.3kJPN
chr4:44709841 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

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