PDB ID 221P CHAINA
Protein nameH-RAS P21 PROTEIN
Uniprot Accession P01112
The number of similar proteins 87
The number of binding states 11
The number of binding partners 9
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
221P (CHAIN: A)
1 Monomeric state
2 Q07889
3 Q07889 Q07889
4 P20936
5 P48736
6 P28829
7 Q9HBX6
8 Q03386
9 P01112
10 P01112 P01112
11 2UZI 2UZI
Downdload
Format:
Molecule viewer
#binding
partners
  8
  7
  6
  5
  4
  3
  2
  1
  0
Sequence information
1  MTEYKLVVVG   AGGVGKSALT   IQLIQNHFVD   EYDPTIEESY   RKQVVIDGET   50
51  CLLDILDTAG   QEEYSAMRDQ   YMRTGEGFLC   VFAINNTKSF   EDIHQYREQI   100
101  KRVKDSDDVP   MVLVGNKCDL   AARTVESRQA   QDLARSYGIP   YIETSAKTRQ   150
151  GVEDAFYTLV   REIRQH                                         200
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
12_GLY ASP VAR_068816 rs104894230 Disease Costello syndrome (CSTLO) [MIM:218040]
13_GLY ARG VAR_068817 rs104894228 Disease Schimmelpenning-Feuerstein-Mims syndrome (SFM) [MIM:163200]
22_GLN LYS VAR_045977 rs121917757 Disease Congenital myopathy with excess of muscle spindles (CMEMS) [MIM:218040]
58_THR ILE VAR_045978 rs121917758 Disease Costello syndrome (CSTLO) [MIM:218040]
61_GLN LYS VAR_045979 rs28933406 Disease Thyroid cancer, non-medullary, 2 (NMTC2) [MIM:188470]
63_GLU LYS VAR_045980 rs121917756 Disease Congenital myopathy with excess of muscle spindles (CMEMS) [MIM:218040]
89_SER CYS VAR_078259 rs755322824 Unclassified -
117_LYS ARG VAR_045981 rs104894227 Disease Costello syndrome (CSTLO) [MIM:218040]
146_ALA VAL VAR_045983 rs121917759 Disease Costello syndrome (CSTLO) [MIM:218040]