PDB ID 2AX2 CHAINA
Protein nameCARBONIC ANHYDRASE II
Uniprot Accession P00918
The number of similar proteins 238
The number of binding states 2
The number of binding partners 1
Coloring
Unicolor (beige)
The number of binding partners
Group

Binding
state
Binding partners
2AX2 (CHAIN: A)
1 Monomeric state
2 1g6vK
Downdload
Format:
Molecule viewer
#binding
partners
  1
  0
Sequence information
1  MSHHWGYGKH   NGPEHWHKDF   PIAKGERQSP   VDIDTHTAKY   DPSLKPLSVS   50
51  YDQATSLRIL   NNGHAFNVEF   DDSQDKAVLK   GGPLDGTYRL   IQFHFHWGSL   100
101  DGQGSEHTVD   KKKYAAELHL   VHWNTKYGDF   GKAVQQPDGL   AVLGIFLKVG   150
151  SAKPGLQKVV   DVLDSIKTKG   KSADFTNFDP   RGLLPESLDY   WTYPGSLTTP   200
201  PLLECVTWIV   LKEPISVSSE   QVLKFRKLNF   NGEGEPEELM   VDNWRPAQPL   250
251  KNRQIKASFK                                                  300
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
18_LYS GLU VAR_001380 rs118203931 Polymorphism -
92_GLN PRO VAR_001381 - Disease Osteopetrosis, autosomal recessive 3 (OPTB3) [MIM:259730]
94_HIS TYR VAR_021009 - Disease Osteopetrosis, autosomal recessive 3 (OPTB3) [MIM:259730]
107_HIS TYR VAR_001382 rs118203933 Disease Osteopetrosis, autosomal recessive 3 (OPTB3) [MIM:259730]
145_GLY ARG VAR_021010 - Disease Osteopetrosis, autosomal recessive 3 (OPTB3) [MIM:259730]
237_PRO HIS VAR_001383 rs118203932 Polymorphism -
253_ASN ASP VAR_001384 rs2228063 Polymorphism -