PDB ID 2DC5     CHAIN A
Protein name Glutathione S-transferase, mu 7
GenBank ID 30354091
The number of similar proteins 2
The number of binding states 1
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2DC5 (CHAIN: A)
1 30354091  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   GSSGSSGXPX   TLGYWDIRGL   AHAIRLFLEY   TDSSYEEKRY   TXGDAPDYDQ   50
51   SQWLNEKFKL   GLDFPNLPYL   IDGSHKITQS   NAILRYLGRK   HNLCGETEEE   100
101   RIRVDILENQ   LXDNRXVLAR   LCYNADFEKL   KPGYLEQLPG   XXRLYSEFLG   150
151   KRPWFAGDKI   TFVDFIAYDV   LERNQVFEAK   CLDAFPNLKD   FIARFEGLKK   200
201   ISDYXKTSRF   LPRPXFTKXA   TWGSNSGPSS   G     250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
8_MET ILE 8.3kJPN
chr1:110210740 		rs201905887
- 0.0049 -
16_ASP GLU gnomAD
chr1:110230522 		rs184653774
- 0.000136455 -
19_GLY ARG 8.3kJPN
chr1:110230529 		-
- 0.0004 -
21_ALA VAL 8.3kJPN
chr1:110255244 		-
- 0.0001 -
22_HIS GLN gnomAD
chr1:110230800 		rs567320393
- 0.000920852 -
23_ALA VAL gnomAD
chr1:110230802 		rs536289169
- 0.000482946 -
25_ARG HIS gnomAD
chr1:110211063 		rs145910843
- 0.00136 -
33_SER TER 8.3kJPN
chr1:110211087 		-
- 0.0001 -
33_SER LEU 8.3kJPN
chr1:110255280 		-
- 0.0001 -
37_GLU LYS 8.3kJPN
chr1:110230843 		rs1259669984
- 0.0001 -
39_LYS TER 8.3kJPN
chr1:110211104 		rs556730458
- 0.0002 -
41_THR ALA gnomAD
chr1:110211110 		rs755629589
- 0.000115318 -
41_THR ALA 8.3kJPN
chr1:110211110 		rs755629589
- 0.0011 -
41_THR MET 8.3kJPN
chr1:110255304 		rs540779576
- 0.0002 -
47_ASP TYR 8.3kJPN
chr1:110211552 		-
- 0.0001 -
66_ASN SER 8.3kJPN
chr1:110211610 		rs371911407
- 0.0084 -
71_ILE MET gnomAD
chr1:110256120 		rs142675425
- 0.000425454 -
72_ASP ASN 8.3kJPN
chr1:110256121 		-
- 0.0001 -
74_THR ALA gnomAD
chr1:110211933 		rs2227960
- 0.00151891 -
74_ALA THR gnomAD
chr1:110256127 		rs17854972
- 0.0830589 -
74_ALA THR 8.3kJPN
chr1:110256127 		rs17854972
- 0.0002 -
84_LEU PRO 8.3kJPN
chr1:110256158 		rs1360731264
- 0.0001 -
85_ARG CYS gnomAD
chr1:110256160 		rs147739570
- 0.000127244 -
85_ARG CYS 8.3kJPN
chr1:110256160 		rs147739570
- 0.0001 -
89_ARG CYS gnomAD
chr1:110231736 		rs781451004
- 0.000679769 -
89_ARG HIS 8.3kJPN
chr1:110211979 		rs769666982
- 0.0003 -
92_ASN SER gnomAD
chr1:110231746 		rs147668562
- 0.0381248 -
92_ASN LYS gnomAD
chr1:110231747 		rs146668816
- 0.000219242 -
103_ARG PRO gnomAD
chr1:110212120 		rs140675803
- 0.000174978 -
103_ARG PRO 8.3kJPN
chr1:110212120 		rs140675803
- 0.0005 -
103_ARG LEU 8.3kJPN
chr1:110231874 		rs199816990
- 0.013 -
103_ARG LEU 8.3kJPN
chr1:110256310 		rs148956224
- 0.0071 -
111_VAL ILE 8.3kJPN
chr1:110256333 		rs756521706
- 0.0002 -
111_VAL ALA 8.3kJPN
chr1:110256334 		rs766842191
- 0.0002 -
112_MET THR 8.3kJPN
chr1:110231901 		rs202002774
- 0.0187 -
112_MET THR 8.3kJPN
chr1:110256337 		rs1326916949
- 0.0002 -
113_ASP GLU 8.3kJPN
chr1:110212151 		-
- 0.0001 -
114_ASN LYS gnomAD
chr1:110256344 		rs144915668
- 0.000107421 -
118_LEU VAL 8.3kJPN
chr1:110256354 		-
- 0.0001 -
119_GLY VAL 8.3kJPN
chr1:110231922 		rs1179816349
- 0.0129 -
121_LEU GLN gnomAD
chr1:110256364 		rs144530836
- 0.00100068 -
124_ASN HIS 8.3kJPN
chr1:110231936 		rs1363667431
- 0.0108 -
146_SER LEU 8.3kJPN
chr1:110257624 		-
- 0.0001 -
152_ARG TRP gnomAD
chr1:110232965 		rs142484086
- 0.0015642 -
152_ARG TRP gnomAD
chr1:110257641 		rs140499099
- 0.00949151 -
152_ARG TRP 8.3kJPN
chr1:110232965 		rs142484086
- 0.0003 -
152_ARG TRP 8.3kJPN
chr1:110257641 		rs140499099
- 0.0075 -
154_TRP ARG gnomAD
chr1:110257647 		rs150881777
- 0.00026244 -
154_TRP TER 8.3kJPN
chr1:110213989 		-
- 0.0001 -
156_LEU ILE 8.3kJPN
chr1:110213993 		-
- 0.0014 -
158_ASN ASP gnomAD
chr1:110232983 		rs140584594
- 0.00174608 -
159_LYS GLU 8.3kJPN
chr1:110257662 		rs778331898
- 0.0011 -
166_LEU VAL gnomAD
chr1:110233094 		rs138440339
- 0.00031646 -
169_ASP VAL gnomAD
chr1:110233104 		rs544766466
- 0.000483405 -
171_LEU ARG 8.3kJPN
chr1:110257786 		-
- 0.0001 -
173_LEU ILE gnomAD
chr1:110233115 		rs149344762
- 0.0143247 -
174_HIS ASN gnomAD
chr1:110233118 		rs146001438
- 0.0154707 -
174_HIS GLN gnomAD
chr1:110233120 		rs143315534
- 0.0188043 -
175_ARG CYS gnomAD
chr1:110233121 		rs375154572
- 0.000186931 -
175_ARG CYS 8.3kJPN
chr1:110257797 		rs761981861
- 0.0017 -
180_LYS ASN gnomAD
chr1:110233138 		rs1065411
- 0.361675 -
180_LYS ASN gnomAD
chr1:110257814 		rs78955679
- 0.00598021 -
180_SER ASN 8.3kJPN
chr1:110214156 		rs2229050
- 0.0001 -
180_LYS ARG 8.3kJPN
chr1:110233137 		rs769295127
- 0.0005 -
180_LYS ASN 8.3kJPN
chr1:110233138 		rs1065411
- 0.7472 -
180_LYS ASN 8.3kJPN
chr1:110257814 		rs78955679
- 0.0743 -
184_ALA VAL gnomAD
chr1:110257825 		rs376313197
- 0.000119296 -
186_LEU PRO gnomAD
chr1:110257831 		rs2227963
- 0.0873792 -
188_LEU VAL 8.3kJPN
chr1:110214179 		-
- 0.0001 -
191_PHE LEU 8.3kJPN
chr1:110214190 		rs1557958959
- 0.0001 -
193_SER PHE 8.3kJPN
chr1:110214195 		-
- 0.0001 -
194_ARG HIS gnomAD
chr1:110233179 		rs753904217
- 0.000192694 -
194_ARG CYS gnomAD
chr1:110257854 		rs150417585
- 0.00560247 -
194_ARG HIS gnomAD
chr1:110257855 		rs137869431
- 0.000159048 -
209_ARG HIS 8.3kJPN
chr1:110235865 		rs371247780
- 0.0001 -
212_ARG TER 8.3kJPN
chr1:110260004 		rs181150599
- 0.0012 -
213_ARG LYS 8.3kJPN
chr1:110217418 		rs527715023
- 0.0005 -
217_SER THR 8.3kJPN
chr1:110235888 		rs449856
- 0.0029 -
218_LYS ARG 8.3kJPN
chr1:110260023 		-
- 0.0001 -
220_ALA VAL gnomAD
chr1:110217439 		rs201667505
- 0.000139172 -
224_SER GLY gnomAD
chr1:110260040 		rs113130058
- 0.00813648 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.